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Page 1
Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration.
Croteau D, Rossi SS, Best BM, Capparelli E, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Grant I, Letendre S; CHARTER Group. Croteau D, et al. Among authors: clifford db. J Antimicrob Chemother. 2013 Mar;68(3):684-9. doi: 10.1093/jac/dks441. Epub 2012 Nov 9. J Antimicrob Chemother. 2013. PMID: 23143899 Free PMC article.
Efavirenz concentrations in CSF exceed IC50 for wild-type HIV.
Best BM, Koopmans PP, Letendre SL, Capparelli EV, Rossi SS, Clifford DB, Collier AC, Gelman BB, Mbeo G, McCutchan JA, Simpson DM, Haubrich R, Ellis R, Grant I; CHARTER Group. Best BM, et al. Among authors: clifford db. J Antimicrob Chemother. 2011 Feb;66(2):354-7. doi: 10.1093/jac/dkq434. Epub 2010 Nov 23. J Antimicrob Chemother. 2011. PMID: 21098541 Free PMC article.
Low cerebrospinal fluid concentrations of the nucleotide HIV reverse transcriptase inhibitor, tenofovir.
Best BM, Letendre SL, Koopmans P, Rossi SS, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Simpson DM, Capparelli EV, Ellis RJ, Grant I; CHARTER Study Group. Best BM, et al. Among authors: clifford db. J Acquir Immune Defic Syndr. 2012 Apr 1;59(4):376-81. doi: 10.1097/QAI.0b013e318247ec54. J Acquir Immune Defic Syndr. 2012. PMID: 22217676 Free PMC article.
Therapeutic amprenavir concentrations in cerebrospinal fluid.
Croteau D, Letendre S, Best BM, Rossi SS, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Way L, Capparelli E, Grant I; CHARTER Group. Croteau D, et al. Among authors: clifford db. Antimicrob Agents Chemother. 2012 Apr;56(4):1985-9. doi: 10.1128/AAC.05098-11. Epub 2012 Jan 30. Antimicrob Agents Chemother. 2012. PMID: 22290964 Free PMC article.
Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration.
Croteau D, Best BM, Letendre S, Rossi SS, Ellis RJ, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S, Grant I; CHARTER Group. Croteau D, et al. Among authors: clifford db. AIDS. 2012 Apr 24;26(7):890-3. doi: 10.1097/QAD.0b013e328351f627. AIDS. 2012. PMID: 22313954 Free PMC article.
Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study.
Livelli A, Vaida F, Ellis RJ, Ma Q, Ferrara M, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Sacktor N, Simpson DM, Grant I, Letendre SL; CHARTER Group. Livelli A, et al. Among authors: clifford db. Lancet HIV. 2019 Jul;6(7):e456-e462. doi: 10.1016/S2352-3018(19)30143-2. Epub 2019 Jun 14. Lancet HIV. 2019. PMID: 31208949
Etravirine in CSF is highly protein bound.
Nguyen A, Rossi S, Croteau D, Best BM, Clifford D, Collier AC, Gelman B, Marra C, McArthur J, McCutchan JA, Morgello S, Simpson D, Ellis RJ, Grant I, Capparelli E, Letendre S; CHARTER Group. Nguyen A, et al. J Antimicrob Chemother. 2013 May;68(5):1161-8. doi: 10.1093/jac/dks517. Epub 2013 Jan 20. J Antimicrob Chemother. 2013. PMID: 23335197 Free PMC article.
Low atazanavir concentrations in cerebrospinal fluid.
Best BM, Letendre SL, Brigid E, Clifford DB, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Simpson DM, Ellis R, Capparelli EV, Grant I; CHARTER Group. Best BM, et al. Among authors: clifford db. AIDS. 2009 Jan 2;23(1):83-7. doi: 10.1097/QAD.0b013e328317a702. AIDS. 2009. PMID: 19050389 Free PMC article. Clinical Trial.
Prevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy.
Anderson AM, Muñoz-Moreno JA, McClernon DR, Ellis RJ, Cookson D, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Sacktor N, Simpson DM, Franklin DR, Heaton RK, Grant I, Letendre SL; CHARTER Group. Anderson AM, et al. Among authors: clifford db. J Infect Dis. 2017 Jan 1;215(1):105-113. doi: 10.1093/infdis/jiw505. Epub 2016 Oct 26. J Infect Dis. 2017. PMID: 27789723 Free PMC article.
Higher buccal mitochondrial DNA and mitochondrial common deletion number are associated with markers of neurodegeneration and inflammation in cerebrospinal fluid.
Solanky D, Fields JA, Iudicello JE, Ellis RJ, Franklin D, Clifford DB, Gelman BB, Marra CM, Morgello S, Rubin LH, Grant I, Heaton RK, Letendre SL, Mehta SR. Solanky D, et al. Among authors: clifford db. J Neurovirol. 2022 Apr;28(2):281-290. doi: 10.1007/s13365-022-01052-9. Epub 2022 Feb 14. J Neurovirol. 2022. PMID: 35157246 Free PMC article.
297 results