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Anti-cocaine vaccine based on coupling a cocaine analog to a disrupted adenovirus.
Koob G, Hicks MJ, Wee S, Rosenberg JB, De BP, Kaminsky SM, Moreno A, Janda KD, Crystal RG. Koob G, et al. Among authors: rosenberg jb. CNS Neurol Disord Drug Targets. 2011 Dec;10(8):899-904. doi: 10.2174/187152711799219334. CNS Neurol Disord Drug Targets. 2011. PMID: 22229312 Free PMC article. Review.
Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.
Maoz A, Hicks MJ, Vallabhjosula S, Synan M, Kothari PJ, Dyke JP, Ballon DJ, Kaminsky SM, De BP, Rosenberg JB, Martinez D, Koob GF, Janda KD, Crystal RG. Maoz A, et al. Among authors: rosenberg jb. Neuropsychopharmacology. 2013 Oct;38(11):2170-8. doi: 10.1038/npp.2013.114. Epub 2013 May 10. Neuropsychopharmacology. 2013. PMID: 23660705 Free PMC article.
Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats.
Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG. Kaminsky SM, et al. Among authors: rosenberg jb. Hum Gene Ther Clin Dev. 2013 Mar;24(1):38-46. doi: 10.1089/humc.2013.054. Hum Gene Ther Clin Dev. 2013. PMID: 23692382
100 results