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Synthesis and biological evaluation (in vitro and in vivo) of cyclic arginine-glycine-aspartate (RGD) peptidomimetic-paclitaxel conjugates targeting integrin αVβ3.
Colombo R, Mingozzi M, Belvisi L, Arosio D, Piarulli U, Carenini N, Perego P, Zaffaroni N, De Cesare M, Castiglioni V, Scanziani E, Gennari C. Colombo R, et al. Among authors: de cesare m. J Med Chem. 2012 Dec 13;55(23):10460-74. doi: 10.1021/jm301058f. Epub 2012 Nov 19. J Med Chem. 2012. PMID: 23140358
Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.
Pilkington-Miksa M, Arosio D, Battistini L, Belvisi L, De Matteo M, Vasile F, Burreddu P, Carta P, Rassu G, Perego P, Carenini N, Zunino F, De Cesare M, Castiglioni V, Scanziani E, Scolastico C, Casiraghi G, Zanardi F, Manzoni L. Pilkington-Miksa M, et al. Among authors: de matteo m, de cesare m. Bioconjug Chem. 2012 Aug 15;23(8):1610-22. doi: 10.1021/bc300164t. Epub 2012 Jul 20. Bioconjug Chem. 2012. PMID: 22770429
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization.
Lecis D, Mastrangelo E, Belvisi L, Bolognesi M, Civera M, Cossu F, De Cesare M, Delia D, Drago C, Manenti G, Manzoni L, Milani M, Moroni E, Perego P, Potenza D, Rizzo V, Scavullo C, Scolastico C, Servida F, Vasile F, Seneci P. Lecis D, et al. Among authors: de cesare m. Bioorg Med Chem. 2012 Nov 15;20(22):6709-23. doi: 10.1016/j.bmc.2012.09.041. Epub 2012 Sep 24. Bioorg Med Chem. 2012. PMID: 23062821
Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.
Carbone A, Pennati M, Parrino B, Lopergolo A, Barraja P, Montalbano A, Spanò V, Sbarra S, Doldi V, De Cesare M, Cirrincione G, Diana P, Zaffaroni N. Carbone A, et al. Among authors: de cesare m. J Med Chem. 2013 Sep 12;56(17):7060-72. doi: 10.1021/jm400842x. Epub 2013 Aug 23. J Med Chem. 2013. PMID: 23919303
FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models.
Corno C, Stucchi S, De Cesare M, Carenini N, Stamatakos S, Ciusani E, Minoli L, Scanziani E, Argueta C, Landesman Y, Zaffaroni N, Gatti L, Perego P. Corno C, et al. Among authors: de cesare m. Biochem Pharmacol. 2018 Jan;147:93-103. doi: 10.1016/j.bcp.2017.11.009. Epub 2017 Nov 16. Biochem Pharmacol. 2018. PMID: 29155058
Novel 7-substituted camptothecins with potent antitumor activity.
Dallavalle S, Delsoldato T, Ferrari A, Merlini L, Penco S, Carenini N, Perego P, De Cesare M, Pratesi G, Zunino F. Dallavalle S, et al. Among authors: de cesare m. J Med Chem. 2000 Oct 19;43(21):3963-9. doi: 10.1021/jm000944z. J Med Chem. 2000. PMID: 11052801
Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.
Dallavalle S, Ferrari A, Merlini L, Penco S, Carenini N, De Cesare M, Perego P, Pratesi G, Zunino F. Dallavalle S, et al. Among authors: de cesare m. Bioorg Med Chem Lett. 2001 Feb 12;11(3):291-4. doi: 10.1016/s0960-894x(00)00649-1. Bioorg Med Chem Lett. 2001. PMID: 11212094
157 results