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Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors.
Li W, Sun W, Zhang Y, Wei W, Ambasudhan R, Xia P, Talantova M, Lin T, Kim J, Wang X, Kim WR, Lipton SA, Zhang K, Ding S. Li W, et al. Among authors: ambasudhan r. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8299-304. doi: 10.1073/pnas.1014041108. Epub 2011 Apr 27. Proc Natl Acad Sci U S A. 2011. PMID: 21525408 Free PMC article.
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, Sason H, Stouffer DG, Buczynski MW, Solomon JP, Michael S, Powers ET, Kelly JW, Roberts A, Tong G, Fang-Newmeyer T, Parker J, Holland EA, Zhang D, Nakanishi N, Chen HS, Wolosker H, Wang Y, Parsons LH, Ambasudhan R, Masliah E, Heinemann SF, Piña-Crespo JC, Lipton SA. Talantova M, et al. Among authors: ambasudhan r. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2518-27. doi: 10.1073/pnas.1306832110. Epub 2013 Jun 17. Proc Natl Acad Sci U S A. 2013. PMID: 23776240 Free PMC article.
Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription.
Ryan SD, Dolatabadi N, Chan SF, Zhang X, Akhtar MW, Parker J, Soldner F, Sunico CR, Nagar S, Talantova M, Lee B, Lopez K, Nutter A, Shan B, Molokanova E, Zhang Y, Han X, Nakamura T, Masliah E, Yates JR 3rd, Nakanishi N, Andreyev AY, Okamoto S, Jaenisch R, Ambasudhan R, Lipton SA. Ryan SD, et al. Among authors: ambasudhan r. Cell. 2013 Dec 5;155(6):1351-64. doi: 10.1016/j.cell.2013.11.009. Epub 2013 Nov 27. Cell. 2013. PMID: 24290359 Free PMC article.
Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells.
Zhu S, Ambasudhan R, Sun W, Kim HJ, Talantova M, Wang X, Zhang M, Zhang Y, Laurent T, Parker J, Kim HS, Zaremba JD, Saleem S, Sanz-Blasco S, Masliah E, McKercher SR, Cho YS, Lipton SA, Kim J, Ding S. Zhu S, et al. Among authors: ambasudhan r. Cell Res. 2014 Jan;24(1):126-9. doi: 10.1038/cr.2013.156. Epub 2013 Dec 3. Cell Res. 2014. PMID: 24296783 Free PMC article. No abstract available.
33 results