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Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Sukhanova A, Gorin A, Serebriiskii IG, Gabitova L, Zheng H, Restifo D, Egleston BL, Cunningham D, Bagnyukova T, Liu H, Nikonova A, Adams GP, Zhou Y, Yang DH, Mehra R, Burtness B, Cai KQ, Klein-Szanto A, Kratz LE, Kelley RI, Weiner LM, Herman GE, Golemis EA, Astsaturov I. Sukhanova A, et al. Among authors: gorin a. Cancer Discov. 2013 Jan;3(1):96-111. doi: 10.1158/2159-8290.CD-12-0031. Epub 2012 Nov 2. Cancer Discov. 2013. PMID: 23125191 Free PMC article.
Regulation of cholesterol biosynthesis and cancer signaling.
Gorin A, Gabitova L, Astsaturov I. Gorin A, et al. Curr Opin Pharmacol. 2012 Dec;12(6):710-6. doi: 10.1016/j.coph.2012.06.011. Epub 2012 Jul 21. Curr Opin Pharmacol. 2012. PMID: 22824431 Free PMC article. Review.
Molecular pathways: sterols and receptor signaling in cancer.
Gabitova L, Gorin A, Astsaturov I. Gabitova L, et al. Among authors: gorin a. Clin Cancer Res. 2014 Jan 1;20(1):28-34. doi: 10.1158/1078-0432.CCR-13-0122. Epub 2013 Oct 24. Clin Cancer Res. 2014. PMID: 24158702 Free PMC article. Review.
Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR.
Gabitova L, Restifo D, Gorin A, Manocha K, Handorf E, Yang DH, Cai KQ, Klein-Szanto AJ, Cunningham D, Kratz LE, Herman GE, Golemis EA, Astsaturov I. Gabitova L, et al. Among authors: gorin a. Cell Rep. 2015 Sep 22;12(11):1927-38. doi: 10.1016/j.celrep.2015.08.023. Epub 2015 Sep 3. Cell Rep. 2015. PMID: 26344763 Free PMC article.
Family functioning and the implications for adult weight management.
McManus-Shipp KE, Cornelius T, Wojtanowski AC, Leahey T, Foster GD, Gorin AA. McManus-Shipp KE, et al. Among authors: gorin aa. Fam Syst Health. 2024 Sep 16. doi: 10.1037/fsh0000929. Online ahead of print. Fam Syst Health. 2024. PMID: 39283252
Recent tropical Andean glacier retreat is unprecedented in the Holocene.
Gorin AL, Shakun JD, Jones AG, Kennedy TM, Marcott SA, Goehring BM, Zoet LK, Jomelli V, Bromley GRM, Mateo EI, Mark BG, Rodbell DT, Gilbert A, Caffee MW. Gorin AL, et al. Science. 2024 Aug 2;385(6708):517-521. doi: 10.1126/science.adg7546. Epub 2024 Aug 1. Science. 2024. PMID: 39088605
295 results