Layfield R - Search Results

1

The S349T mutation of SQSTM1 links Keap1/Nrf2 signalling to Paget's disease of bone.

Wright T, Rea SL, Goode A, Bennett AJ, Ratajczak T, Long JE, Searle MS, Goldring CE, Park BK, Copple IM, Layfield R. Wright T, et al. Among authors: layfield r. Bone. 2013 Feb;52(2):699-706. doi: 10.1016/j.bone.2012.10.023. Epub 2012 Oct 29. Bone. 2013. PMID: 23117207

2

Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone.

Ciani B, Layfield R, Cavey JR, Sheppard PW, Searle MS. Ciani B, et al. Among authors: layfield r. J Biol Chem. 2003 Sep 26;278(39):37409-12. doi: 10.1074/jbc.M307416200. Epub 2003 Jul 11. J Biol Chem. 2003. PMID: 12857745 Free article.

3

Stability and folding kinetics of a ubiquitin mutant with a strong propensity for nonnative beta-hairpin conformation in the unfolded state.

Platt GW, Simpson SA, Layfield R, Searle MS. Platt GW, et al. Among authors: layfield r. Biochemistry. 2003 Nov 25;42(46):13762-71. doi: 10.1021/bi030147d. Biochemistry. 2003. PMID: 14622023

4

Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences.

Hocking LJ, Lucas GJ, Daroszewska A, Cundy T, Nicholson GC, Donath J, Walsh JP, Finlayson C, Cavey JR, Ciani B, Sheppard PW, Searle MS, Layfield R, Ralston SH. Hocking LJ, et al. Among authors: layfield r. J Bone Miner Res. 2004 Jul;19(7):1122-7. doi: 10.1359/JBMR.0403015. Epub 2004 Mar 22. J Bone Miner Res. 2004. PMID: 15176995 Free article.

5

SQSTM1 and Paget's disease of bone.

Layfield R, Hocking LJ. Layfield R, et al. Calcif Tissue Int. 2004 Nov;75(5):347-57. doi: 10.1007/s00223-004-0041-0. Epub 2004 Sep 16. Calcif Tissue Int. 2004. PMID: 15365659 Review.

6

Structural and functional studies of mutations affecting the UBA domain of SQSTM1 (p62) which cause Paget's disease of bone.

Layfield R, Ciani B, Ralston SH, Hocking LJ, Sheppard PW, Searle MS, Cavey JR. Layfield R, et al. Biochem Soc Trans. 2004 Nov;32(Pt 5):728-30. doi: 10.1042/BST0320728. Biochem Soc Trans. 2004. PMID: 15493999 Review.

7

Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations.

Cavey JR, Ralston SH, Hocking LJ, Sheppard PW, Ciani B, Searle MS, Layfield R. Cavey JR, et al. Among authors: layfield r. J Bone Miner Res. 2005 Apr;20(4):619-24. doi: 10.1359/JBMR.041205. Epub 2004 Dec 6. J Bone Miner Res. 2005. PMID: 15765181 Free article.

8

Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone.

Cavey JR, Ralston SH, Sheppard PW, Ciani B, Gallagher TR, Long JE, Searle MS, Layfield R. Cavey JR, et al. Among authors: layfield r. Calcif Tissue Int. 2006 May;78(5):271-7. doi: 10.1007/s00223-005-1299-6. Epub 2006 May 6. Calcif Tissue Int. 2006. PMID: 16691492

9

p62 mutations, ubiquitin recognition and Paget's disease of bone.

Layfield R, Cavey JR, Najat D, Long J, Sheppard PW, Ralston SH, Searle MS. Layfield R, et al. Biochem Soc Trans. 2006 Nov;34(Pt 5):735-7. doi: 10.1042/BST0340735. Biochem Soc Trans. 2006. PMID: 17052185

10

PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle.

Constantin D, Constantin-Teodosiu D, Layfield R, Tsintzas K, Bennett AJ, Greenhaff PL. Constantin D, et al. Among authors: layfield r. J Physiol. 2007 Aug 15;583(Pt 1):381-90. doi: 10.1113/jphysiol.2007.135459. Epub 2007 May 31. J Physiol. 2007. PMID: 17540700 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

217 results

Search Page