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Preclinical research in Rett syndrome: setting the foundation for translational success.
Katz DM, Berger-Sweeney JE, Eubanks JH, Justice MJ, Neul JL, Pozzo-Miller L, Blue ME, Christian D, Crawley JN, Giustetto M, Guy J, Howell CJ, Kron M, Nelson SB, Samaco RC, Schaevitz LR, St Hillaire-Clarke C, Young JL, Zoghbi HY, Mamounas LA. Katz DM, et al. Among authors: giustetto m. Dis Model Mech. 2012 Nov;5(6):733-45. doi: 10.1242/dmm.011007. Dis Model Mech. 2012. PMID: 23115203 Free PMC article. Review.
Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome-Like Sensorimotor Defects.
Morello N, Schina R, Pilotto F, Phillips M, Melani R, Plicato O, Pizzorusso T, Pozzo-Miller L, Giustetto M. Morello N, et al. Among authors: giustetto m. eNeuro. 2018 Sep 24;5(5):ENEURO.0086-18.2018. doi: 10.1523/ENEURO.0086-18.2018. eCollection 2018 Sep-Oct. eNeuro. 2018. PMID: 30255129 Free PMC article.
JNK signaling provides a novel therapeutic target for Rett syndrome.
Musi CA, Castaldo AM, Valsecchi AE, Cimini S, Morello N, Pizzo R, Renieri A, Meloni I, Bonati M, Giustetto M, Borsello T. Musi CA, et al. Among authors: giustetto m. BMC Biol. 2021 Dec 16;19(1):256. doi: 10.1186/s12915-021-01190-2. BMC Biol. 2021. PMID: 34911542 Free PMC article.
p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P. Repetto D, et al. Among authors: giustetto m. J Neurosci. 2014 Jan 22;34(4):1542-53. doi: 10.1523/JNEUROSCI.2341-13.2014. J Neurosci. 2014. PMID: 24453341 Free PMC article.
mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder.
Gurgone A, Pizzo R, Raspanti A, Chiantia G, Devi S, Comai D, Morello N, Pilotto F, Gnavi S, Lupori L, Mazziotti R, Sagona G, Putignano E, Nocentini A, Supuran CT, Marcantoni A, Pizzorusso T, Giustetto M. Gurgone A, et al. Among authors: giustetto m. Neuropsychopharmacology. 2023 May;48(6):877-886. doi: 10.1038/s41386-022-01412-3. Epub 2022 Aug 9. Neuropsychopharmacology. 2023. PMID: 35945276 Free PMC article.
67 results