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Early antiviral CD4+ and CD8+ T cells are associated with upper airway clearance of SARS-CoV-2.
Ramirez SI, Lopez PG, Faraji F, Parikh UM, Heaps A, Ritz J, Moser C, Eron JJ, Wohl D, Currier J, Daar ES, Greninger A, Klekotka P, Grifoni A, Weiskopf D, Sette A, Peters B, Hughes MD, Chew KW, Smith DM, Crotty S; Accelerating COVID-19 Therapeutic Interventions and Vaccines-2 (ACTIV-2)/A5401 Study Team. Ramirez SI, et al. Among authors: hughes md. JCI Insight. 2024 Dec 20;9(24):e186078. doi: 10.1172/jci.insight.186078. JCI Insight. 2024. PMID: 39704169 Free PMC article.
Erratum: The statistical design and analysis of pandemic platform trials: Implications for the future - CORRIGENDUM.
Lindsell CJ, Shotwell M, Anstrom KJ, Berry S, Brittain E, Harrell FE, Geller N, Grund B, Hughes MD, Jagannathan P, Leifer E, Moser CB, Price KL, Proschan M, Stewart T, Thomas S, Touloumi G, LaVange L. Lindsell CJ, et al. Among authors: hughes md. J Clin Transl Sci. 2024 Oct 28;8(1):e177. doi: 10.1017/cts.2024.648. eCollection 2024. J Clin Transl Sci. 2024. PMID: 39619071 Free PMC article.
The statistical design and analysis of pandemic platform trials: Implications for the future.
Lindsell CJ, Shotwell M, Anstrom KJ, Berry S, Brittain E, Harrell FE, Geller N, Grund B, Hughes MD, Jagannathan P, Leifer E, Moser CB, Price KL, Proschan M, Stewart T, Thomas S, Touloumi G, LaVange L. Lindsell CJ, et al. Among authors: hughes md. J Clin Transl Sci. 2024 Oct 15;8(1):e155. doi: 10.1017/cts.2024.514. eCollection 2024. J Clin Transl Sci. 2024. PMID: 39540110 Free PMC article.
ACTIV trials: Lessons learned in trial design in the setting of an emergent pandemic.
Keshtkar-Jahromi M, Anstrom KJ, Barkauskas C, Brown SM, Daar ES, Fischer W, Gibbs KW, Higgs ES, Hughes MD, Jagannathan P, LaVange L, Lindsell CJ, Nayak SU, Paredes R, Parmar M, Peltan ID, Proschan M, Shotwell MS, Vock DM, Yokum T, Adam SJ. Keshtkar-Jahromi M, et al. Among authors: hughes md. J Clin Transl Sci. 2024 Oct 15;8(1):e151. doi: 10.1017/cts.2024.1. eCollection 2024. J Clin Transl Sci. 2024. PMID: 39478775 Free PMC article. Review.
Mortality and Associated Risk Factors Among People Living With HIV With Kaposi Sarcoma: A5263/AMC066 and A5264/AMC067.
Chagomerana MB, Moser CB, Kang M, Umbleja T, Hughes MD, Campbell TB, Krown SE, Borok MZ, Samaneka W, Ngongondo M, Nyirenda M, Langat DC, Hoagland B, Burger H, Busakhala N, Njiru E, Mwelase N, Mngqibisa R, Hosseinipour MC. Chagomerana MB, et al. Among authors: hughes md. J Acquir Immune Defic Syndr. 2024 Nov 1;97(3):216-225. doi: 10.1097/QAI.0000000000003484. J Acquir Immune Defic Syndr. 2024. PMID: 39431505 Clinical Trial.
Post-acute COVID-19 outcomes including participant-reported long COVID: amubarvimab/romlusevimab versus placebo in the ACTIV-2 trial.
Evering TH, Moser C, Jilg N, Ritz J, Wohl DA, Li JZ, Margolis D, Javan AC, Eron JJ, Currier JS, Daar ES, Smith DM, Hughes MD, Chew KW; ACTIV-2/A5401 Study Team. Evering TH, et al. Among authors: hughes md. EClinicalMedicine. 2024 Aug 16;75:102787. doi: 10.1016/j.eclinm.2024.102787. eCollection 2024 Sep. EClinicalMedicine. 2024. PMID: 39252866 Free PMC article.
SARS-CoV-2 Monoclonal Antibody Treatment Followed by Vaccination Shifts Human Memory B-Cell Epitope Recognition, Suggesting Antibody Feedback.
Bloom N, Ramirez SI, Cohn H, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Bajic G, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S, Coelho CH; Accelerating COVID-19 Therapeutic Interventions and Vaccines–2/A5401 (ACTIV-2/A5401) Study Team. Bloom N, et al. Among authors: hughes md. J Infect Dis. 2024 Nov 15;230(5):1187-1196. doi: 10.1093/infdis/jiae371. J Infect Dis. 2024. PMID: 39036987 Clinical Trial.
320 results