Schofield CJ - Search Results

1

Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.

Sánchez-Fernández EM, Tarhonskaya H, Al-Qahtani K, Hopkinson RJ, McCullagh JS, Schofield CJ, Flashman E. Sánchez-Fernández EM, et al. Among authors: schofield cj. Biochem J. 2013 Jan 15;449(2):491-6. doi: 10.1042/BJ20121155. Biochem J. 2013. PMID: 23092293 Free PMC article.

2

Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis.

Lawrence CC, Sobey WJ, Field RA, Baldwin JE, Schofield CJ. Lawrence CC, et al. Among authors: schofield cj. Biochem J. 1996 Jan 1;313 ( Pt 1)(Pt 1):185-91. doi: 10.1042/bj3130185. Biochem J. 1996. PMID: 8546682 Free PMC article.

3

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes.

Schofield CJ, Zhang Z. Schofield CJ, et al. Curr Opin Struct Biol. 1999 Dec;9(6):722-31. doi: 10.1016/s0959-440x(99)00036-6. Curr Opin Struct Biol. 1999. PMID: 10607676 Review.

4

Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate.

Long AJ, Clifton IJ, Roach PL, Baldwin JE, Schofield CJ, Rutledge PJ. Long AJ, et al. Among authors: schofield cj. Biochem J. 2003 Jun 15;372(Pt 3):687-93. doi: 10.1042/BJ20021627. Biochem J. 2003. PMID: 12622704 Free PMC article.

5

The role of iron and 2-oxoglutarate oxygenases in signalling.

Hewitson KS, McNeill LA, Elkins JM, Schofield CJ. Hewitson KS, et al. Among authors: schofield cj. Biochem Soc Trans. 2003 Jun;31(Pt 3):510-5. doi: 10.1042/bst0310510. Biochem Soc Trans. 2003. PMID: 12773146 Review.

6

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.

Lancaster DE, McNeill LA, McDonough MA, Aplin RT, Hewitson KS, Pugh CW, Ratcliffe PJ, Schofield CJ. Lancaster DE, et al. Among authors: schofield cj. Biochem J. 2004 Nov 1;383(Pt. 3):429-37. doi: 10.1042/BJ20040735. Biochem J. 2004. PMID: 15239670 Free PMC article.

7

X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster.

Elkins JM, Kershaw NJ, Schofield CJ. Elkins JM, et al. Among authors: schofield cj. Biochem J. 2005 Jan 15;385(Pt 2):565-73. doi: 10.1042/BJ20040814. Biochem J. 2005. PMID: 15352873 Free PMC article.

8

OS-9: another piece in the HIF complex story.

Flashman E, McDonough MA, Schofield CJ. Flashman E, et al. Among authors: schofield cj. Mol Cell. 2005 Feb 18;17(4):472-3. doi: 10.1016/j.molcel.2005.02.001. Mol Cell. 2005. PMID: 15721249 Free article. Review.

9

Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

Hewitson KS, Granatino N, Welford RW, McDonough MA, Schofield CJ. Hewitson KS, et al. Among authors: schofield cj. Philos Trans A Math Phys Eng Sci. 2005 Apr 15;363(1829):807-28; discussion 1035-40. doi: 10.1098/rsta.2004.1540. Philos Trans A Math Phys Eng Sci. 2005. PMID: 15901537 Review.

10

Signalling hypoxia by HIF hydroxylases.

Schofield CJ, Ratcliffe PJ. Schofield CJ, et al. Biochem Biophys Res Commun. 2005 Dec 9;338(1):617-26. doi: 10.1016/j.bbrc.2005.08.111. Epub 2005 Aug 24. Biochem Biophys Res Commun. 2005. PMID: 16139242 Review.

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