Gupta M - Search Results

1

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun.

Sundaresan NR, Vasudevan P, Zhong L, Kim G, Samant S, Parekh V, Pillai VB, Ravindra PV, Gupta M, Jeevanandam V, Cunningham JM, Deng CX, Lombard DB, Mostoslavsky R, Gupta MP. Sundaresan NR, et al. Among authors: gupta mp, gupta m. Nat Med. 2012 Nov;18(11):1643-50. doi: 10.1038/nm.2961. Epub 2012 Oct 21. Nat Med. 2012. PMID: 23086477 Free PMC article.

2

Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway.

Pillai VB, Sundaresan NR, Kim G, Gupta M, Rajamohan SB, Pillai JB, Samant S, Ravindra PV, Isbatan A, Gupta MP. Pillai VB, et al. Among authors: gupta mp, gupta m. J Biol Chem. 2010 Jan 29;285(5):3133-44. doi: 10.1074/jbc.M109.077271. Epub 2009 Nov 24. J Biol Chem. 2010. PMID: 19940131 Free PMC article.

3

Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy.

Sundaresan NR, Pillai VB, Gupta MP. Sundaresan NR, et al. J Mol Cell Cardiol. 2011 Oct;51(4):614-8. doi: 10.1016/j.yjmcc.2011.01.008. Epub 2011 Jan 27. J Mol Cell Cardiol. 2011. PMID: 21276800 Free PMC article. Review.

4

The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.

Sundaresan NR, Pillai VB, Wolfgeher D, Samant S, Vasudevan P, Parekh V, Raghuraman H, Cunningham JM, Gupta M, Gupta MP. Sundaresan NR, et al. Among authors: gupta mp, gupta m. Sci Signal. 2011 Jul 19;4(182):ra46. doi: 10.1126/scisignal.2001465. Sci Signal. 2011. PMID: 21775285

5

Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling.

Pillai VB, Sundaresan NR, Kim G, Samant S, Moreno-Vinasco L, Garcia JG, Gupta MP. Pillai VB, et al. Am J Physiol Heart Circ Physiol. 2013 Feb 1;304(3):H415-26. doi: 10.1152/ajpheart.00468.2012. Epub 2012 Nov 30. Am J Physiol Heart Circ Physiol. 2013. PMID: 23203961 Free PMC article.

6

A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.

Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M. Nagalingam RS, et al. Among authors: gupta mp, gupta m. J Biol Chem. 2013 Apr 19;288(16):11216-32. doi: 10.1074/jbc.M112.442384. Epub 2013 Feb 27. J Biol Chem. 2013. Retraction in: J Biol Chem. 2017 Mar 24;292(12):5123. doi: 10.1074/jbc.A112.442384 PMID: 23447532 Free PMC article. Retracted.

We have previously shown that miR-378 regulates cardiac growth during the postnatal period by direct targeting of IGF1R (Knezevic, I., Patel, A., Sundaresan, N. R., Gupta, M. P., Solaro, R. J., Nagalingam, R. S., and Gupta, M. (2012) J. Biol. Chem. 287 …

We have previously shown that miR-378 regulates cardiac growth during the postnatal period by direct targeting of IGF1R (Knezevic, I., Patel …

7

Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.

Pillai VB, Sundaresan NR, Gupta MP. Pillai VB, et al. Circ Res. 2014 Jan 17;114(2):368-78. doi: 10.1161/CIRCRESAHA.113.300536. Circ Res. 2014. PMID: 24436432 Free PMC article. Review.

8

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.

Pillai VB, Samant S, Sundaresan NR, Raghuraman H, Kim G, Bonner MY, Arbiser JL, Walker DI, Jones DP, Gius D, Gupta MP. Pillai VB, et al. Nat Commun. 2015 Apr 14;6:6656. doi: 10.1038/ncomms7656. Nat Commun. 2015. PMID: 25871545 Free PMC article.

9

The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy.

Pillai VB, Samant S, Hund S, Gupta M, Gupta MP. Pillai VB, et al. Among authors: gupta mp, gupta m. Aging (Albany NY). 2021 May 2;13(9):12334-12358. doi: 10.18632/aging.203027. Epub 2021 May 2. Aging (Albany NY). 2021. PMID: 33934090 Free PMC article.

10

Skeletal muscle-specific over-expression of the nuclear sirtuin SIRT6 blocks cancer-associated cachexia by regulating multiple targets.

Samant SA, Pillai VB, Gupta MP. Samant SA, et al. JCSM Rapid Commun. 2021 Jan-Jun;4(1):40-56. doi: 10.1002/rco2.27. Epub 2020 Dec 23. JCSM Rapid Commun. 2021. PMID: 34212132 Free PMC article.

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