Brandt M - Search Results

1

Steroidal A ring aryl carboxylic acids: a new class of steroid 5 alpha-reductase inhibitors.

Holt DA, Levy MA, Ladd DL, Oh HJ, Erb JM, Heaslip JI, Brandt M, Metcalf BW. Holt DA, et al. Among authors: brandt m. J Med Chem. 1990 Mar;33(3):937-42. doi: 10.1021/jm00165a009. J Med Chem. 1990. PMID: 2308144

2

Mechanistic studies with solubilized rat liver steroid 5 alpha-reductase: elucidation of the kinetic mechanism.

Levy MA, Brandt M, Greway AT. Levy MA, et al. Among authors: brandt m. Biochemistry. 1990 Mar 20;29(11):2808-15. doi: 10.1021/bi00463a025. Biochemistry. 1990. PMID: 2140700

3

Studies on the mechanism of steroid 5 alpha-reductase inhibition by 3-carboxy A-ring aryl steroids.

Brandt M, Greway AT, Holt DA, Metcalf BW, Levy MA. Brandt M, et al. J Steroid Biochem Mol Biol. 1990 Nov 30;37(4):575-9. doi: 10.1016/0960-0760(90)90403-8. J Steroid Biochem Mol Biol. 1990. PMID: 2278842

4

Inhibition of steroid 5 alpha-reductase by unsaturated 3-carboxysteroids.

Holt DA, Levy MA, Oh HJ, Erb JM, Heaslip JI, Brandt M, Lan-Hargest HY, Metcalf BW. Holt DA, et al. Among authors: brandt m. J Med Chem. 1990 Mar;33(3):943-50. doi: 10.1021/jm00165a010. J Med Chem. 1990. PMID: 2308145

5

Inhibition of rat liver steroid 5 alpha-reductase by 3-androstene-3-carboxylic acids: mechanism of enzyme-inhibitor interaction.

Levy MA, Brandt M, Heys JR, Holt DA, Metcalf BW. Levy MA, et al. Among authors: brandt m. Biochemistry. 1990 Mar 20;29(11):2815-24. doi: 10.1021/bi00463a026. Biochemistry. 1990. PMID: 2346747

6

Interaction between rat prostatic steroid 5 alpha-reductase and 3-carboxy-17 beta-substituted steroids: novel mechanism of enzyme inhibition.

Levy MA, Brandt M, Holt DA, Metcalf BW. Levy MA, et al. Among authors: brandt m. J Steroid Biochem. 1989;34(1-6):571-5. doi: 10.1016/0022-4731(89)90148-9. J Steroid Biochem. 1989. PMID: 2626051

7

Inhibition of pyridine-nucleotide-dependent enzymes by pyrazoles. Synthesis and enzymology of a novel A-ring pyrazole steroid.

Holt DA, Levy MA, Brandt M, Metcalf BW. Holt DA, et al. Among authors: brandt m. Steroids. 1986 Sep-Oct;48(3-4):213-22. doi: 10.1016/0039-128x(86)90004-8. Steroids. 1986. PMID: 3481887

8

Cloning, expression and functional characterization of type 1 and type 2 steroid 5 alpha-reductases from Cynomolgus monkey: comparisons with human and rat isoenzymes.

Levy MA, Brandt M, Sheedy KM, Holt DA, Heaslip JI, Trill JJ, Ryan PJ, Morris RA, Garrison LM, Bergsma DJ. Levy MA, et al. Among authors: brandt m. J Steroid Biochem Mol Biol. 1995 Apr;52(4):307-19. doi: 10.1016/0960-0760(94)00183-m. J Steroid Biochem Mol Biol. 1995. PMID: 7734398

9

Benzophenone- and indolecarboxylic acids: potent type-2 specific inhibitors of human steroid 5 alpha-reductase.

Holt DA, Yamashita DS, Konialian-Beck AL, Luengo JI, Abell AD, Bergsma DJ, Brandt M, Levy MA. Holt DA, et al. Among authors: brandt m. J Med Chem. 1995 Jan 6;38(1):13-5. doi: 10.1021/jm00001a004. J Med Chem. 1995. PMID: 7837223 No abstract available.

10

Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2.

Levy MA, Brandt M, Sheedy KM, Dinh JT, Holt DA, Garrison LM, Bergsma DJ, Metcalf BW. Levy MA, et al. Among authors: brandt m. J Steroid Biochem Mol Biol. 1994 Feb;48(2-3):197-206. doi: 10.1016/0960-0760(94)90145-7. J Steroid Biochem Mol Biol. 1994. PMID: 8142295

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