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Page 1
Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes.
Terelius Y, Figler RA, Marukian S, Collado MS, Lawson MJ, Mackey AJ, Manka D, Qualls CW Jr, Blackman BR, Wamhoff BR, Dash A. Terelius Y, et al. Among authors: qualls cw jr. Chem Biol Interact. 2016 Aug 5;255:31-44. doi: 10.1016/j.cbi.2015.11.023. Epub 2015 Dec 2. Chem Biol Interact. 2016. PMID: 26626330 Free PMC article.
An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation.
Cole BK, Simmers MB, Feaver R, Qualls CW Jr, Collado MS, Berzin E, Figler RA, Pryor AW Jr, Lawson M, Mackey A, Manka D, Wamhoff BR, Turk JR, Blackman BR. Cole BK, et al. Among authors: qualls cw jr. Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2185-95. doi: 10.1161/ATVBAHA.115.306245. Epub 2015 Aug 20. Arterioscler Thromb Vasc Biol. 2015. PMID: 26293464
Differential mitochondrial toxicity screening and multi-parametric data analysis.
Tsiper MV, Sturgis J, Avramova LV, Parakh S, Fatig R, Juan-García A, Li N, Rajwa B, Narayanan P, Qualls CW Jr, Robinson JP, Davisson VJ. Tsiper MV, et al. Among authors: qualls cw jr. PLoS One. 2012;7(10):e45226. doi: 10.1371/journal.pone.0045226. Epub 2012 Oct 15. PLoS One. 2012. PMID: 23077490 Free PMC article.
High-throughput secondary screening at the single-cell level.
Robinson JP, Patsekin V, Holdman C, Ragheb K, Sturgis J, Fatig R, Avramova LV, Rajwa B, Davisson VJ, Lewis N, Narayanan P, Li N, Qualls CW Jr. Robinson JP, et al. Among authors: qualls cw jr. J Lab Autom. 2013 Feb;18(1):85-98. doi: 10.1177/2211068212456978. Epub 2012 Sep 10. J Lab Autom. 2013. PMID: 22968419 Free PMC article.
Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys.
Hoivik DJ, Qualls CW Jr, Mirabile RC, Cariello NF, Kimbrough CL, Colton HM, Anderson SP, Santostefano MJ, Morgan RJ, Dahl RR, Brown AR, Zhao Z, Mudd PN Jr, Oliver WB Jr, Brown HR, Miller RT. Hoivik DJ, et al. Among authors: qualls cw jr. Carcinogenesis. 2004 Sep;25(9):1757-69. doi: 10.1093/carcin/bgh182. Epub 2004 May 6. Carcinogenesis. 2004. PMID: 15131011
Effects of minimally toxic levels of carbonyl cyanide P-(trifluoromethoxy) phenylhydrazone (FCCP), elucidated through differential gene expression with biochemical and morphological correlations.
Kuruvilla S, Qualls CW Jr, Tyler RD, Witherspoon SM, Benavides GR, Yoon LW, Dold K, Brown RH, Sangiah S, Morgan KT. Kuruvilla S, et al. Among authors: qualls cw jr. Toxicol Sci. 2003 Jun;73(2):348-61. doi: 10.1093/toxsci/kfg084. Epub 2003 Apr 15. Toxicol Sci. 2003. PMID: 12700400
Application of cDNA microarray technology to in vitro toxicology and the selection of genes for a real-time RT-PCR-based screen for oxidative stress in Hep-G2 cells.
Morgan KT, Ni H, Brown HR, Yoon L, Qualls CW Jr, Crosby LM, Reynolds R, Gaskill B, Anderson SP, Kepler TB, Brainard T, Liv N, Easton M, Merrill C, Creech D, Sprenger D, Conner G, Johnson PR, Fox T, Sartor M, Richard E, Kuruvilla S, Casey W, Benavides G. Morgan KT, et al. Among authors: qualls cw jr. Toxicol Pathol. 2002 Jul-Aug;30(4):435-51. doi: 10.1080/01926230290105613. Toxicol Pathol. 2002. PMID: 12187936
62 results