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Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.
Bergmayr C, Thurner P, Keuerleber S, Kudlacek O, Nanoff C, Freissmuth M, Gruber CW. Bergmayr C, et al. Among authors: gruber cw. J Biol Chem. 2013 Oct 4;288(40):28831-44. doi: 10.1074/jbc.M113.464776. Epub 2013 Aug 21. J Biol Chem. 2013. PMID: 23965991 Free PMC article.
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW. Koehbach J, et al. Among authors: gruber cw. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248349 Free PMC article.
Nature-Derived Peptides: A Growing Niche for GPCR Ligand Discovery.
Muratspahić E, Freissmuth M, Gruber CW. Muratspahić E, et al. Among authors: gruber cw. Trends Pharmacol Sci. 2019 May;40(5):309-326. doi: 10.1016/j.tips.2019.03.004. Epub 2019 Apr 5. Trends Pharmacol Sci. 2019. PMID: 30955896 Free PMC article. Review.
Natural products in drug discovery: advances and opportunities.
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Atanasov AG, et al. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z. Epub 2021 Jan 28. Nat Rev Drug Discov. 2021. PMID: 33510482 Free PMC article. Review.
Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling.
Muratspahić E, Tomašević N, Nasrollahi-Shirazi S, Gattringer J, Emser FS, Freissmuth M, Gruber CW. Muratspahić E, et al. Among authors: gruber cw. J Nat Prod. 2021 Aug 27;84(8):2238-2248. doi: 10.1021/acs.jnatprod.1c00301. Epub 2021 Jul 26. J Nat Prod. 2021. PMID: 34308635 Free PMC article.
115 results