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Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism.
Yabut KCB, Martynova A, Nath A, Zercher BP, Bush MF, Isoherranen N. Yabut KCB, et al. Among authors: isoherranen n. bioRxiv [Preprint]. 2024 Jan 19:2024.01.17.576032. doi: 10.1101/2024.01.17.576032. bioRxiv. 2024. Update in: Mol Pharmacol. 2024 May 17;105(6):395-410. doi: 10.1124/molpharm.124.000878 PMID: 38293009 Free PMC article. Updated. Preprint.
Role of itraconazole metabolites in CYP3A4 inhibition.
Isoherranen N, Kunze KL, Allen KE, Nelson WL, Thummel KE. Isoherranen N, et al. Drug Metab Dispos. 2004 Oct;32(10):1121-31. doi: 10.1124/dmd.104.000315. Epub 2004 Jul 8. Drug Metab Dispos. 2004. PMID: 15242978
Stereochemical aspects of itraconazole metabolism in vitro and in vivo.
Kunze KL, Nelson WL, Kharasch ED, Thummel KE, Isoherranen N. Kunze KL, et al. Among authors: isoherranen n. Drug Metab Dispos. 2006 Apr;34(4):583-90. doi: 10.1124/dmd.105.008508. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415110 Clinical Trial.
Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo.
Templeton IE, Thummel KE, Kharasch ED, Kunze KL, Hoffer C, Nelson WL, Isoherranen N. Templeton IE, et al. Among authors: isoherranen n. Clin Pharmacol Ther. 2008 Jan;83(1):77-85. doi: 10.1038/sj.clpt.6100230. Epub 2007 May 9. Clin Pharmacol Ther. 2008. PMID: 17495874 Free PMC article. Clinical Trial.
The role of CYP26 enzymes in retinoic acid clearance.
Thatcher JE, Isoherranen N. Thatcher JE, et al. Among authors: isoherranen n. Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):875-86. doi: 10.1517/17425250903032681. Expert Opin Drug Metab Toxicol. 2009. PMID: 19519282 Free PMC article. Review.
171 results