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The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes.
Mori H, Ikegami H, Kawaguchi Y, Seino S, Yokoi N, Takeda J, Inoue I, Seino Y, Yasuda K, Hanafusa T, Yamagata K, Awata T, Kadowaki T, Hara K, Yamada N, Gotoda T, Iwasaki N, Iwamoto Y, Sanke T, Nanjo K, Oka Y, Matsutani A, Maeda E, Kasuga M. Mori H, et al. Among authors: seino y, seino s. Diabetes. 2001 Apr;50(4):891-4. doi: 10.2337/diabetes.50.4.891. Diabetes. 2001. PMID: 11289058
Roles of cAMP signalling in insulin granule exocytosis.
Seino S, Takahashi H, Fujimoto W, Shibasaki T. Seino S, et al. Diabetes Obes Metab. 2009 Nov;11 Suppl 4:180-8. doi: 10.1111/j.1463-1326.2009.01108.x. Diabetes Obes Metab. 2009. PMID: 19817800 Review.
[Regulatory mechanism of incretin secretion].
Shibasaki T, Seino S. Shibasaki T, et al. Among authors: seino s. Nihon Rinsho. 2011 May;69(5):803-7. Nihon Rinsho. 2011. PMID: 21595262 Japanese.
[Roles of the cAMP sensor Epac2A in insulin secretion].
Shibasaki T, Seino S. Shibasaki T, et al. Among authors: seino s. Nihon Naika Gakkai Zasshi. 2011 May 10;100(5):1418-24. doi: 10.2169/naika.100.1418. Nihon Naika Gakkai Zasshi. 2011. PMID: 21702163 Review. Japanese. No abstract available.
639 results