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A dominant-negative mutation of HSF2 associated with idiopathic azoospermia.
Mou L, Wang Y, Li H, Huang Y, Jiang T, Huang W, Li Z, Chen J, Xie J, Liu Y, Jiang Z, Li X, Ye J, Cai Z, Gui Y. Mou L, et al. Among authors: jiang t, jiang z. Hum Genet. 2013 Feb;132(2):159-65. doi: 10.1007/s00439-012-1234-7. Epub 2012 Oct 14. Hum Genet. 2013. PMID: 23064888
Excess of rare variants in genes that are key epigenetic regulators of spermatogenesis in the patients with non-obstructive azoospermia.
Li Z, Huang Y, Li H, Hu J, Liu X, Jiang T, Sun G, Tang A, Sun X, Qian W, Zeng Y, Xie J, Zhao W, Xu Y, He T, Dong C, Liu Q, Mou L, Lu J, Lin Z, Wu S, Gao S, Guo G, Feng Q, Li Y, Zhang X, Wang J, Yang H, Wang J, Xiong C, Cai Z, Gui Y. Li Z, et al. Among authors: jiang t. Sci Rep. 2015 Mar 5;5:8785. doi: 10.1038/srep08785. Sci Rep. 2015. PMID: 25739334 Free PMC article.
Novel Y-chromosomal microdeletions associated with non-obstructive azoospermia uncovered by high throughput sequencing of sequence-tagged sites (STSs).
Liu X, Li Z, Su Z, Zhang J, Li H, Xie J, Xu H, Jiang T, Luo L, Zhang R, Zeng X, Xu H, Huang Y, Mou L, Hu J, Qian W, Zeng Y, Zhang X, Xiong C, Yang H, Kristiansen K, Cai Z, Wang J, Gui Y. Liu X, et al. Among authors: jiang t. Sci Rep. 2016 Feb 24;6:21831. doi: 10.1038/srep21831. Sci Rep. 2016. PMID: 26907467 Free PMC article.
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma.
Guo G, Gui Y, Gao S, Tang A, Hu X, Huang Y, Jia W, Li Z, He M, Sun L, Song P, Sun X, Zhao X, Yang S, Liang C, Wan S, Zhou F, Chen C, Zhu J, Li X, Jian M, Zhou L, Ye R, Huang P, Chen J, Jiang T, Liu X, Wang Y, Zou J, Jiang Z, Wu R, Wu S, Fan F, Zhang Z, Liu L, Yang R, Liu X, Wu H, Yin W, Zhao X, Liu Y, Peng H, Jiang B, Feng Q, Li C, Xie J, Lu J, Kristiansen K, Li Y, Zhang X, Li S, Wang J, Yang H, Cai Z, Wang J. Guo G, et al. Among authors: jiang t, jiang b, jiang z. Nat Genet. 2011 Dec 4;44(1):17-9. doi: 10.1038/ng.1014. Nat Genet. 2011. PMID: 22138691
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.
Wang XN, Li ZS, Ren Y, Jiang T, Wang YQ, Chen M, Zhang J, Hao JX, Wang YB, Sha RN, Huang Y, Liu X, Hu JC, Sun GQ, Li HG, Xiong CL, Xie J, Jiang ZM, Cai ZM, Wang J, Wang J, Huff V, Gui YT, Gao F. Wang XN, et al. Among authors: jiang t, jiang zm. PLoS Genet. 2013;9(8):e1003645. doi: 10.1371/journal.pgen.1003645. Epub 2013 Aug 1. PLoS Genet. 2013. PMID: 23935527 Free PMC article.
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.
Li Y, Vinckenbosch N, Tian G, Huerta-Sanchez E, Jiang T, Jiang H, Albrechtsen A, Andersen G, Cao H, Korneliussen T, Grarup N, Guo Y, Hellman I, Jin X, Li Q, Liu J, Liu X, Sparsø T, Tang M, Wu H, Wu R, Yu C, Zheng H, Astrup A, Bolund L, Holmkvist J, Jørgensen T, Kristiansen K, Schmitz O, Schwartz TW, Zhang X, Li R, Yang H, Wang J, Hansen T, Pedersen O, Nielsen R, Wang J. Li Y, et al. Among authors: jiang t, jiang h. Nat Genet. 2010 Nov;42(11):969-72. doi: 10.1038/ng.680. Epub 2010 Oct 3. Nat Genet. 2010. PMID: 20890277
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