Vuorinen A - Search Results

1

Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action.

Nashev LG, Vuorinen A, Praxmarer L, Chantong B, Cereghetti D, Winiger R, Schuster D, Odermatt A. Nashev LG, et al. Among authors: vuorinen a. PLoS One. 2012;7(10):e46958. doi: 10.1371/journal.pone.0046958. Epub 2012 Oct 4. PLoS One. 2012. PMID: 23056542 Free PMC article.

2

In silico methods in the discovery of endocrine disrupting chemicals.

Vuorinen A, Odermatt A, Schuster D. Vuorinen A, et al. J Steroid Biochem Mol Biol. 2013 Sep;137:18-26. doi: 10.1016/j.jsbmb.2013.04.009. Epub 2013 May 17. J Steroid Biochem Mol Biol. 2013. PMID: 23688835 Review.

3

Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11β-hydroxysteroid dehydrogenase type 2.

Kratschmar DV, Vuorinen A, Da Cunha T, Wolber G, Classen-Houben D, Doblhoff O, Schuster D, Odermatt A. Kratschmar DV, et al. Among authors: vuorinen a. J Steroid Biochem Mol Biol. 2011 May;125(1-2):129-42. doi: 10.1016/j.jsbmb.2010.12.019. Epub 2011 Jan 12. J Steroid Biochem Mol Biol. 2011. PMID: 21236343

4

The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation.

Fürstenberger C, Vuorinen A, Da Cunha T, Kratschmar DV, Saugy M, Schuster D, Odermatt A. Fürstenberger C, et al. Among authors: vuorinen a. Toxicol Sci. 2012 Apr;126(2):353-61. doi: 10.1093/toxsci/kfs022. Epub 2012 Jan 23. Toxicol Sci. 2012. PMID: 22273746

5

Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1.

Meyer A, Vuorinen A, Zielinska AE, Da Cunha T, Strajhar P, Lavery GG, Schuster D, Odermatt A. Meyer A, et al. Among authors: vuorinen a. Biochem Pharmacol. 2013 May 1;85(9):1370-8. doi: 10.1016/j.bcp.2013.02.014. Epub 2013 Feb 16. Biochem Pharmacol. 2013. PMID: 23419873

6

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

Meyer A, Vuorinen A, Zielinska AE, Strajhar P, Lavery GG, Schuster D, Odermatt A. Meyer A, et al. Among authors: vuorinen a. Drug Metab Dispos. 2013 Sep;41(9):1671-8. doi: 10.1124/dmd.113.052936. Epub 2013 Jun 26. Drug Metab Dispos. 2013. PMID: 23804523 Free PMC article.

7

Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid.

Penno CA, Morgan SA, Vuorinen A, Schuster D, Lavery GG, Odermatt A. Penno CA, et al. Among authors: vuorinen a. J Lipid Res. 2013 Oct;54(10):2874-83. doi: 10.1194/jlr.M042499. Epub 2013 Aug 9. J Lipid Res. 2013. PMID: 23933573 Free PMC article.

8

Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors.

Vuorinen A, Engeli R, Meyer A, Bachmann F, Griesser UJ, Schuster D, Odermatt A. Vuorinen A, et al. J Med Chem. 2014 Jul 24;57(14):5995-6007. doi: 10.1021/jm5004914. Epub 2014 Jul 10. J Med Chem. 2014. PMID: 24960438 Free PMC article.

9

Methods for generating and applying pharmacophore models as virtual screening filters and for bioactivity profiling.

Vuorinen A, Schuster D. Vuorinen A, et al. Methods. 2015 Jan;71:113-34. doi: 10.1016/j.ymeth.2014.10.013. Epub 2014 Oct 22. Methods. 2015. PMID: 25461773 Review.

10

Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1.

Vuorinen A, Seibert J, Papageorgiou VP, Rollinger JM, Odermatt A, Schuster D, Assimopoulou AN. Vuorinen A, et al. Planta Med. 2015 Apr;81(6):525-32. doi: 10.1055/s-0035-1545720. Epub 2015 Mar 17. Planta Med. 2015. PMID: 25782037

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