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Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons.
Diniz LP, Almeida JC, Tortelli V, Vargas Lopes C, Setti-Perdigão P, Stipursky J, Kahn SA, Romão LF, de Miranda J, Alves-Leon SV, de Souza JM, Castro NG, Panizzutti R, Gomes FC. Diniz LP, et al. Among authors: tortelli v. J Biol Chem. 2012 Nov 30;287(49):41432-45. doi: 10.1074/jbc.M112.380824. Epub 2012 Oct 10. J Biol Chem. 2012. PMID: 23055518 Free PMC article.
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model.
Diniz LP, Tortelli V, Matias I, Morgado J, Bérgamo Araujo AP, Melo HM, Seixas da Silva GS, Alves-Leon SV, de Souza JM, Ferreira ST, De Felice FG, Gomes FCA. Diniz LP, et al. Among authors: tortelli v. J Neurosci. 2017 Jul 12;37(28):6797-6809. doi: 10.1523/JNEUROSCI.3351-16.2017. Epub 2017 Jun 12. J Neurosci. 2017. PMID: 28607171 Free PMC article.
Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers.
Pitt J, Wilcox KC, Tortelli V, Diniz LP, Oliveira MS, Dobbins C, Yu XW, Nandamuri S, Gomes FCA, DiNunno N, Viola KL, De Felice FG, Ferreira ST, Klein WL. Pitt J, et al. Among authors: tortelli v. Mol Biol Cell. 2017 Oct 1;28(20):2623-2636. doi: 10.1091/mbc.E17-06-0416. Epub 2017 Aug 9. Mol Biol Cell. 2017. PMID: 28963439 Free PMC article.