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Skin hepcidin initiates psoriasiform skin inflammation via Fe-driven hyperproliferation and neutrophil recruitment.
Abboud E, Chrayteh D, Boussetta N, Dalle H, Malerba M, Wu TD, Le Gall M, Reelfs O, Pourzand C, Mellett M, Assan F, Bachelez H, Poupon J, Aractingi S, Vaulont S, Sohier P, Oules B, Karim Z, Peyssonnaux C. Abboud E, et al. Among authors: mellett m. Nat Commun. 2024 Aug 7;15(1):6718. doi: 10.1038/s41467-024-50993-8. Nat Commun. 2024. PMID: 39112467 Free PMC article.
Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation.
Kurgyis Z, Vornholz L, Pechloff K, Kemény LV, Wartewig T, Muschaweckh A, Joshi A, Kranen K, Hartjes L, Möckel S, Steiger K, Hameister E, Volz T, Mellett M, French LE, Biedermann T, Korn T, Ruland J. Kurgyis Z, et al. Among authors: mellett m. Sci Immunol. 2021 Nov 26;6(65):eabi4425. doi: 10.1126/sciimmunol.abi4425. Epub 2021 Nov 26. Sci Immunol. 2021. PMID: 34826258
42 results