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CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation.
Manjarrez-Orduño N, Marasco E, Chung SA, Katz MS, Kiridly JF, Simpfendorfer KR, Freudenberg J, Ballard DH, Nashi E, Hopkins TJ, Cunninghame Graham DS, Lee AT, Coenen MJ, Franke B, Swinkels DW, Graham RR, Kimberly RP, Gaffney PM, Vyse TJ, Behrens TW, Criswell LA, Diamond B, Gregersen PK. Manjarrez-Orduño N, et al. Among authors: diamond b. Nat Genet. 2012 Nov;44(11):1227-30. doi: 10.1038/ng.2439. Epub 2012 Oct 7. Nat Genet. 2012. PMID: 23042117 Free PMC article.
B cell hyporesponsiveness and autoimmunity: a new paradigm.
Grimaldi C, Nashi E, Venkatesh J, Diamond B. Grimaldi C, et al. Among authors: diamond b. Adv Exp Med Biol. 2007;596:181-90. doi: 10.1007/0-387-46530-8_18. Adv Exp Med Biol. 2007. PMID: 17338188 Review. No abstract available.
The role of B cells in lupus pathogenesis.
Nashi E, Wang Y, Diamond B. Nashi E, et al. Among authors: diamond b. Int J Biochem Cell Biol. 2010 Apr;42(4):543-50. doi: 10.1016/j.biocel.2009.10.011. Epub 2009 Oct 20. Int J Biochem Cell Biol. 2010. PMID: 19850148 Free PMC article. Review.
The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development.
Simpfendorfer KR, Olsson LM, Manjarrez Orduño N, Khalili H, Simeone AM, Katz MS, Lee AT, Diamond B, Gregersen PK. Simpfendorfer KR, et al. Among authors: diamond b. Hum Mol Genet. 2012 Sep 1;21(17):3918-25. doi: 10.1093/hmg/dds220. Epub 2012 Jun 7. Hum Mol Genet. 2012. PMID: 22678060 Free PMC article.
A model for lupus brain disease.
Diamond B, Volpe BT. Diamond B, et al. Immunol Rev. 2012 Jul;248(1):56-67. doi: 10.1111/j.1600-065X.2012.01137.x. Immunol Rev. 2012. PMID: 22725954 Free PMC article. Review.
810 results