Komiotis D - Search Results

1

Conformational analysis of two novel cytotoxic C2-substituted pyrrolo[2,3-f]quinolines in aqueous media, organic solvents, membrane bilayers and at the putative active site.

Varvarigou N, Megariotis G, Leonis G, Vrontaki E, Maniati AM, Vlachou M, Eikosipentaki A, Kompogennitaki R, Papadopoulos MG, Grdadolnik SG, Komiotis D, Mavromoustakos T, Tsotinis A. Varvarigou N, et al. Among authors: komiotis d. Bioorg Med Chem. 2012 Nov 1;20(21):6276-84. doi: 10.1016/j.bmc.2012.09.012. Epub 2012 Sep 15. Bioorg Med Chem. 2012. PMID: 23040892

2

Synthesis of diphenoxyadamantane alkylamines with pharmacological interest.

Georgiadis MO, Kourbeli V, Ioannidou V, Karakitsios E, Papanastasiou I, Tsotinis A, Komiotis D, Vocat A, Cole ST, Taylor MC, Kelly JM. Georgiadis MO, et al. Among authors: komiotis d. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1278-1281. doi: 10.1016/j.bmcl.2019.04.010. Epub 2019 Apr 6. Bioorg Med Chem Lett. 2019. PMID: 30981579

3

Branched-chain sugar nucleosides: stereocontrolled synthesis and bioevaluation of novel 3'-C-trifluoromethyl and 3'-C-methyl pyranonucleosides.

Kollatos N, Manta S, Dimopoulou A, Parmenopoulou V, Triantakonstanti VV, Kellici T, Mavromoustakos T, Schols D, Komiotis D. Kollatos N, et al. Among authors: komiotis d. Carbohydr Res. 2015 Apr 30;407:170-8. doi: 10.1016/j.carres.2015.01.021. Epub 2015 Feb 7. Carbohydr Res. 2015. PMID: 25812993

4

Mapping the Melatonin Receptor. 8. Selective MT2 Agonists Derived from 5,6-Dihydroindolo[2,1-a]isoquinolines and Related Systems.

Tsotinis A, Afroudakis PA, Papanastasiou IP, Sakellaropoulou A, Boniakou M, Komiotis D, Garratt PJ, Delagrange P, Bocianowska-Zbrog A, Sugden D. Tsotinis A, et al. Among authors: komiotis d. ChemMedChem. 2022 Jun 20;17(12):e202200129. doi: 10.1002/cmdc.202200129. Epub 2022 May 9. ChemMedChem. 2022. PMID: 35478275

5

1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.

Tsirkone VG, Tsoukala E, Lamprakis C, Manta S, Hayes JM, Skamnaki VT, Drakou C, Zographos SE, Komiotis D, Leonidas DD. Tsirkone VG, et al. Among authors: komiotis d. Bioorg Med Chem. 2010 May 15;18(10):3413-25. doi: 10.1016/j.bmc.2010.04.004. Epub 2010 Apr 7. Bioorg Med Chem. 2010. PMID: 20430629

6

Rapid microwave-enhanced synthesis of C5-alkynyl pyranonucleosides as novel cytotoxic antitumor agents.

Dimopoulou A, Manta S, Kiritsis C, Gkaragkouni DN, Papasotiriou I, Balzarini J, Komiotis D. Dimopoulou A, et al. Among authors: komiotis d. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1330-3. doi: 10.1016/j.bmcl.2012.12.092. Epub 2013 Jan 7. Bioorg Med Chem Lett. 2013. PMID: 23369539

7

An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents.

Tsoukala E, Agelis G, Dolinsek J, Botić T, Cencic A, Komiotis D. Tsoukala E, et al. Among authors: komiotis d. Bioorg Med Chem. 2007 May 1;15(9):3241-7. doi: 10.1016/j.bmc.2007.02.031. Epub 2007 Feb 20. Bioorg Med Chem. 2007. PMID: 17337193

8

Fluoro-ketopyranosyl nucleosides: synthesis and biological evaluation of 3-fluoro-2-keto-beta-D-glucopyranosyl derivatives of N4-benzoyl cytosine.

Manta S, Agelis G, Botić T, Cencic A, Komiotis D. Manta S, et al. Among authors: komiotis d. Bioorg Med Chem. 2007 Jan 15;15(2):980-7. doi: 10.1016/j.bmc.2006.10.033. Epub 2006 Oct 19. Bioorg Med Chem. 2007. PMID: 17079149

9

Exomethylene pyranonucleosides: efficient synthesis and biological evaluation of 1-(2,3,4-trideoxy-2-methylene-beta-d-glycero-hex-3-enopyranosyl)thymine.

Agelis G, Tzioumaki N, Botić T, Cencic A, Komiotis D. Agelis G, et al. Among authors: komiotis d. Bioorg Med Chem. 2007 Aug 15;15(16):5448-56. doi: 10.1016/j.bmc.2007.05.055. Epub 2007 May 26. Bioorg Med Chem. 2007. PMID: 17555969

10

Synthesis of 4,6-dideoxy-3-fluoro-2-keto-beta-D-glucopyranosyl analogues of 5-fluorouracil, N6-benzoyl adenine, uracil, thymine, N4-benzoyl cytosine and evaluation of their antitumor activities.

Manta S, Tsoukala E, Tzioumaki N, Kiritsis C, Balzarini J, Komiotis D. Manta S, et al. Among authors: komiotis d. Bioorg Chem. 2010 Apr;38(2):48-55. doi: 10.1016/j.bioorg.2009.11.001. Epub 2009 Nov 20. Bioorg Chem. 2010. PMID: 20018340

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