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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor.
Duthey B, Caudron S, Perroy J, Bettler B, Fagni L, Pin JP, Prézeau L. Duthey B, et al. Among authors: bettler b. J Biol Chem. 2002 Feb 1;277(5):3236-41. doi: 10.1074/jbc.M108900200. Epub 2001 Nov 15. J Biol Chem. 2002. PMID: 11711539 Free PMC article.
Among the GPCRs, the gamma-aminobutyric acid (GABA) type B receptor (GABA(B)R) is the only one known so far that needs two subunits, GB1 and GB2, to function. ...In contrast the GB2 subunit, which does not bind GABA, has an heptahelical domain able to activate G-pro …
Among the GPCRs, the gamma-aminobutyric acid (GABA) type B receptor (GABA(B)R) is the only one known so far that needs two sub …
Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.
Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, Gentry C, Jaton AL, Van der Putten H, Mombereau C, Lecourtier L, Mosbacher J, Cryan JF, Fritschy JM, Lüthi A, Kaupmann K, Bettler B. Gassmann M, et al. Among authors: bettler b. J Neurosci. 2004 Jul 7;24(27):6086-97. doi: 10.1523/JNEUROSCI.5635-03.2004. J Neurosci. 2004. PMID: 15240800 Free PMC article.
Floxed allele for conditional inactivation of the GABAB(1) gene.
Haller C, Casanova E, Müller M, Vacher CM, Vigot R, Doll T, Barbieri S, Gassmann M, Bettler B. Haller C, et al. Among authors: bettler b. Genesis. 2004 Nov;40(3):125-30. doi: 10.1002/gene.20073. Genesis. 2004. PMID: 15493018
205 results