Sun L - Search Results

1

Ultrasensitive liquid chromatography-tandem mass spectrometric methodologies for quantification of five HIV-1 integrase inhibitors in plasma for a microdose clinical trial.

Sun L, Li H, Willson K, Breidinger S, Rizk ML, Wenning L, Woolf EJ. Sun L, et al. Anal Chem. 2012 Oct 16;84(20):8614-21. doi: 10.1021/ac301581h. Epub 2012 Oct 2. Anal Chem. 2012. PMID: 23030780 Clinical Trial.

2

Quantitative determination of odanacatib in human plasma using liquid-liquid extraction followed by liquid chromatography-tandem mass spectrometry analysis.

Sun L, Forni S, Schwartz MS, Breidinger S, Woolf EJ. Sun L, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Feb 15;885-886:15-23. doi: 10.1016/j.jchromb.2011.12.004. Epub 2011 Dec 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22230741

3

Insulin glargine and its two active metabolites: A sensitive (16pM) and robust simultaneous hybrid assay coupling immunoaffinity purification with LC-MS/MS to support biosimilar clinical studies.

Xu Y, Sun L, Anderson M, Bélanger P, Trinh V, Lavallée P, Kantesaria B, Marcoux MJ, Breidinger S, Bateman KP, Goykhman D, Woolf EJ. Xu Y, et al. Among authors: sun l. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:50-59. doi: 10.1016/j.jchromb.2017.08.018. Epub 2017 Aug 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28846865

4

Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma.

Sun L, Xu Y, Dube N, Anderson M, Breidinger S, Vaddady P, Thornton B, Morrow L, Matthews RP, Stoch SA, Woolf EJ. Sun L, et al. J Pharm Biomed Anal. 2022 Apr 1;212:114639. doi: 10.1016/j.jpba.2022.114639. Epub 2022 Feb 2. J Pharm Biomed Anal. 2022. PMID: 35176654

5

Toward highly sensitive and reproducible LC-MS/MS analysis of MK-8591 phosphorylated anabolites in human peripheral blood mononuclear cells.

Sun L, Chavez-Eng C, Fillgrove KL, Lu B, Xie I, Rudd DJ, Breidinger S, Anderson M, Yeh S, Zhang R, Woolf EJ. Sun L, et al. Bioanalysis. 2019 Feb;11(4):233-250. doi: 10.4155/bio-2018-0101. Epub 2019 Feb 15. Bioanalysis. 2019. PMID: 30767560

6

An in vivo microdialysis coupled with liquid chromatography/tandem mass spectrometry study of cortisol metabolism in monkey adipose tissue.

Sun L, Stenken JA, Brunner JE, Michel KB, Adelsberger JK, Yang AY, Zhao JJ, Musson DG. Sun L, et al. Anal Biochem. 2008 Oct 15;381(2):214-23. doi: 10.1016/j.ab.2008.06.036. Epub 2008 Jul 2. Anal Biochem. 2008. PMID: 18638442

7

Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.

Wright DH, Stone JA, Crumley TM, Wenning L, Zheng W, Yan K, Yang AY, Sun L, Cilissen C, Ramael S, Hermanowski-Vosatka A, Langdon RB, Gottesdiener KM, Wagner JA, Lai E. Wright DH, et al. Among authors: sun l. Br J Clin Pharmacol. 2013 Dec;76(6):917-31. doi: 10.1111/bcp.12131. Br J Clin Pharmacol. 2013. PMID: 23594227 Free PMC article. Clinical Trial.

8

Determination of M+4 stable isotope labeled cortisone and cortisol in human plasma by microElution solid-phase extraction and liquid chromatography/tandem mass spectrometry.

Yang AY, Sun L, Musson DG, Zhao JJ. Yang AY, et al. Among authors: sun l. Rapid Commun Mass Spectrom. 2006;20(2):233-40. doi: 10.1002/rcm.2303. Rapid Commun Mass Spectrom. 2006. PMID: 16345110

9

The effect of beta-cyclodextrin on liquid chromatography/electrospray-mass spectrometry analysis of hydrophobic drug molecules.

Sun L, Stenken JA. Sun L, et al. J Chromatogr A. 2007 Aug 17;1161(1-2):261-8. doi: 10.1016/j.chroma.2007.05.104. Epub 2007 Jun 13. J Chromatogr A. 2007. PMID: 17599341

10

An in vitro microdialysis methodology to study 11beta-hydroxysteroid dehydrogenase type 1 enzyme activity in liver microsomes.

Sun L, Stenken JA, Yang AY, Zhao JJ, Musson DG. Sun L, et al. Anal Biochem. 2007 Nov 1;370(1):26-37. doi: 10.1016/j.ab.2007.06.038. Epub 2007 Jun 28. Anal Biochem. 2007. PMID: 17765862

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