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TALEN-based gene correction for epidermolysis bullosa.
Osborn MJ, Starker CG, McElroy AN, Webber BR, Riddle MJ, Xia L, DeFeo AP, Gabriel R, Schmidt M, von Kalle C, Carlson DF, Maeder ML, Joung JK, Wagner JE, Voytas DF, Blazar BR, Tolar J. Osborn MJ, et al. Mol Ther. 2013 Jun;21(6):1151-9. doi: 10.1038/mt.2013.56. Epub 2013 Apr 2. Mol Ther. 2013. PMID: 23546300 Free PMC article.
Fanconi anemia gene editing by the CRISPR/Cas9 system.
Osborn MJ, Gabriel R, Webber BR, DeFeo AP, McElroy AN, Jarjour J, Starker CG, Wagner JE, Joung JK, Voytas DF, von Kalle C, Schmidt M, Blazar BR, Tolar J. Osborn MJ, et al. Hum Gene Ther. 2015 Feb;26(2):114-26. doi: 10.1089/hum.2014.111. Hum Gene Ther. 2015. PMID: 25545896 Free PMC article.
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases.
Osborn MJ, Webber BR, Knipping F, Lonetree CL, Tennis N, DeFeo AP, McElroy AN, Starker CG, Lee C, Merkel S, Lund TC, Kelly-Spratt KS, Jensen MC, Voytas DF, von Kalle C, Schmidt M, Gabriel R, Hippen KL, Miller JS, Scharenberg AM, Tolar J, Blazar BR. Osborn MJ, et al. Mol Ther. 2016 Mar;24(3):570-81. doi: 10.1038/mt.2015.197. Epub 2015 Oct 27. Mol Ther. 2016. PMID: 26502778 Free PMC article.
Gene editing and its application for hematological diseases.
Osborn MJ, Belanto JJ, Tolar J, Voytas DF. Osborn MJ, et al. Int J Hematol. 2016 Jul;104(1):18-28. doi: 10.1007/s12185-016-2017-z. Epub 2016 May 27. Int J Hematol. 2016. PMID: 27233509 Free PMC article. Review.
Sarcoma derived from cultured mesenchymal stem cells.
Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, Prockop DJ, Fibbe WE, Blazar BR. Tolar J, et al. Among authors: osborn mj. Stem Cells. 2007 Feb;25(2):371-9. doi: 10.1634/stemcells.2005-0620. Epub 2006 Oct 12. Stem Cells. 2007. PMID: 17038675
211 results