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Page 1
Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors.
Liu T, Nair SJ, Lescarbeau A, Belani J, Peluso S, Conley J, Tillotson B, O'Hearn P, Smith S, Slocum K, West K, Helble J, Douglas M, Bahadoor A, Ali J, McGovern K, Fritz C, Palombella VJ, Wylie A, Castro AC, Tremblay MR. Liu T, et al. Among authors: belani j. J Med Chem. 2012 Oct 25;55(20):8859-78. doi: 10.1021/jm3011542. Epub 2012 Oct 12. J Med Chem. 2012. PMID: 23025805
The discovery of N-((2H-tetrazol-5-yl)methyl)-4-((R)-1-((5r,8R)-8-(tert-butyl)-3-(3,5-dichlorophenyl)-2-oxo-1,4-diazaspiro[4.5]dec-3-en-1-yl)-4,4-dimethylpentyl)benzamide (SCH 900822): a potent and selective glucagon receptor antagonist.
DeMong D, Dai X, Hwa J, Miller M, Lin SI, Kang L, Stamford A, Greenlee W, Yu W, Wong M, Lavey B, Kozlowski J, Zhou G, Yang DY, Patel B, Soriano A, Zhai Y, Sondey C, Zhang H, Lachowicz J, Grotz D, Cox K, Morrison R, Andreani T, Cao Y, Liang M, Meng T, McNamara P, Wong J, Bradley P, Feng KI, Belani J, Chen P, Dai P, Gauuan J, Lin P, Zhao H. DeMong D, et al. Among authors: belani j. J Med Chem. 2014 Mar 27;57(6):2601-10. doi: 10.1021/jm401858f. Epub 2014 Feb 26. J Med Chem. 2014. PMID: 24527772
A concise synthesis of ent-Cholesterol.
Belani JD, Rychnovsky SD. Belani JD, et al. J Org Chem. 2008 Apr 4;73(7):2768-73. doi: 10.1021/jo702694g. Epub 2008 Mar 13. J Org Chem. 2008. PMID: 18336043 Free PMC article.
Dual roles for cholesterol in mammalian cells.
Xu F, Rychnovsky SD, Belani JD, Hobbs HH, Cohen JC, Rawson RB. Xu F, et al. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14551-6. doi: 10.1073/pnas.0503590102. Epub 2005 Sep 30. Proc Natl Acad Sci U S A. 2005. PMID: 16199524 Free PMC article.
27 results