Payton MA - Search Results

1

The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial.

Horak F, Zieglmayer P, Zieglmayer R, Lemell P, Collins LP, Hunter MG, Steiner J, Lewis T, Payton MA, Perkins CM, Pettipher R. Horak F, et al. Among authors: payton ma. Allergy. 2012 Dec;67(12):1572-9. doi: 10.1111/all.12042. Epub 2012 Oct 1. Allergy. 2012. PMID: 23025511 Clinical Trial.

2

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459.

Pettipher R, Hunter MG, Perkins CM, Collins LP, Lewis T, Baillet M, Steiner J, Bell J, Payton MA. Pettipher R, et al. Among authors: payton ma. Allergy. 2014 Sep;69(9):1223-32. doi: 10.1111/all.12451. Epub 2014 Jul 14. Allergy. 2014. PMID: 24866478 Clinical Trial.

3

A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma.

Barnes N, Pavord I, Chuchalin A, Bell J, Hunter M, Lewis T, Parker D, Payton M, Collins LP, Pettipher R, Steiner J, Perkins CM. Barnes N, et al. Clin Exp Allergy. 2012 Jan;42(1):38-48. doi: 10.1111/j.1365-2222.2011.03813.x. Epub 2011 Jul 15. Clin Exp Allergy. 2012. PMID: 21762224 Clinical Trial.

4

Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis.

Straumann A, Hoesli S, Bussmann Ch, Stuck M, Perkins M, Collins LP, Payton M, Pettipher R, Hunter M, Steiner J, Simon HU. Straumann A, et al. Allergy. 2013 Mar;68(3):375-85. doi: 10.1111/all.12096. Epub 2013 Feb 5. Allergy. 2013. PMID: 23379537 Clinical Trial.

5

Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils.

Pettipher R, Vinall SL, Xue L, Speight G, Townsend ER, Gazi L, Whelan CJ, Armer RE, Payton MA, Hunter MG. Pettipher R, et al. Among authors: payton ma. J Pharmacol Exp Ther. 2012 Feb;340(2):473-82. doi: 10.1124/jpet.111.187203. Epub 2011 Nov 21. J Pharmacol Exp Ther. 2012. PMID: 22106101

6

Cross reactivity between IA-2 and phogrin/IA-2beta in binding of autoantibodies in IDDM.

Hatfield EC, Hawkes CJ, Payton MA, Christie MR. Hatfield EC, et al. Among authors: payton ma. Diabetologia. 1997 Nov;40(11):1327-33. doi: 10.1007/s001250050828. Diabetologia. 1997. PMID: 9389426

7

Combined screening for autoantibodies to IA-2 and antibodies to glutamic acid decarboxylase in first degree relatives of patients with IDDM. The DENIS Study Group. Deutsche Nikotinamid Interventions-Studie.

Seissler J, Morgenthaler NG, Achenbach P, Lampeter EF, Glawe D, Payton M, Christie M, Scherbaum WA. Seissler J, et al. Diabetologia. 1996 Nov;39(11):1351-6. doi: 10.1007/s001250050582. Diabetologia. 1996. PMID: 8933004

8

Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).

Payton MA, Hawkes CJ, Christie MR. Payton MA, et al. J Clin Invest. 1995 Sep;96(3):1506-11. doi: 10.1172/JCI118188. J Clin Invest. 1995. PMID: 7657822 Free PMC article.

9

Validity of screening for individuals at risk for type I diabetes by combined analysis of antibodies to recombinant proteins.

Christie MR, Roll U, Payton MA, Hatfield EC, Ziegler AG. Christie MR, et al. Among authors: payton ma. Diabetes Care. 1997 Jun;20(6):965-70. doi: 10.2337/diacare.20.6.965. Diabetes Care. 1997. PMID: 9167107

10

Antibodies to the tyrosine phosphatase-like protein IA-2 are highly associated with IDDM, but not with autoimmune endocrine diseases or stiff man syndrome.

Morgenthaler NG, Seissler J, Achenbach P, Glawe D, Payton M, Meinck HM, Christie MR, Scherbaum WA. Morgenthaler NG, et al. Autoimmunity. 1997;25(4):203-11. doi: 10.3109/08916939708994729. Autoimmunity. 1997. PMID: 9344328 Free article.

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