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Caspase-14-deficient mice are more prone to the development of parakeratosis.
Hoste E, Denecker G, Gilbert B, Van Nieuwerburgh F, van der Fits L, Asselbergh B, De Rycke R, Hachem JP, Deforce D, Prens EP, Vandenabeele P, Declercq W. Hoste E, et al. Among authors: denecker g. J Invest Dermatol. 2013 Mar;133(3):742-750. doi: 10.1038/jid.2012.350. Epub 2012 Sep 27. J Invest Dermatol. 2013. PMID: 23014340 Free article.
Caspase-14 protects against epidermal UVB photodamage and water loss.
Denecker G, Hoste E, Gilbert B, Hochepied T, Ovaere P, Lippens S, Van den Broecke C, Van Damme P, D'Herde K, Hachem JP, Borgonie G, Presland RB, Schoonjans L, Libert C, Vandekerckhove J, Gevaert K, Vandenabeele P, Declercq W. Denecker G, et al. Nat Cell Biol. 2007 Jun;9(6):666-74. doi: 10.1038/ncb1597. Epub 2007 May 21. Nat Cell Biol. 2007. PMID: 17515931
Caspase-14 reveals its secrets.
Denecker G, Ovaere P, Vandenabeele P, Declercq W. Denecker G, et al. J Cell Biol. 2008 Feb 11;180(3):451-8. doi: 10.1083/jcb.200709098. Epub 2008 Feb 4. J Cell Biol. 2008. PMID: 18250198 Free PMC article. Review.
The "caveolae brake hypothesis" and the epidermal barrier.
Roelandt T, Giddelo C, Heughebaert C, Denecker G, Hupe M, Crumrine D, Kusuma A, Haftek M, Roseeuw D, Declercq W, Feingold KR, Elias PM, Hachem JP. Roelandt T, et al. Among authors: denecker g. J Invest Dermatol. 2009 Apr;129(4):927-36. doi: 10.1038/jid.2008.328. Epub 2008 Nov 13. J Invest Dermatol. 2009. PMID: 19005485 Free article.
Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin.
Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W. Hoste E, et al. Among authors: denecker g. J Invest Dermatol. 2011 Nov;131(11):2233-41. doi: 10.1038/jid.2011.153. Epub 2011 Jun 9. J Invest Dermatol. 2011. PMID: 21654840 Free article.
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Devos M, Gilbert B, Denecker G, Leurs K, Mc Guire C, Lemeire K, Hochepied T, Vuylsteke M, Lambert J, Van Den Broecke C, Libbrecht L, Haigh J, Berx G, Lippens S, Vandenabeele P, Declercq W. Devos M, et al. Among authors: denecker g. J Invest Dermatol. 2017 Feb;137(2):494-505. doi: 10.1016/j.jid.2016.09.026. Epub 2016 Oct 7. J Invest Dermatol. 2017. PMID: 27725202 Free article.
Death penalty for keratinocytes: apoptosis versus cornification.
Lippens S, Denecker G, Ovaere P, Vandenabeele P, Declercq W. Lippens S, et al. Among authors: denecker g. Cell Death Differ. 2005 Nov;12 Suppl 2:1497-508. doi: 10.1038/sj.cdd.4401722. Cell Death Differ. 2005. PMID: 16247497 Review.
A novel caspase-2 complex containing TRAF2 and RIP1.
Lamkanfi M, D'hondt K, Vande Walle L, van Gurp M, Denecker G, Demeulemeester J, Kalai M, Declercq W, Saelens X, Vandenabeele P. Lamkanfi M, et al. Among authors: denecker g. J Biol Chem. 2005 Feb 25;280(8):6923-32. doi: 10.1074/jbc.M411180200. Epub 2004 Dec 8. J Biol Chem. 2005. PMID: 15590671 Free article.
61 results