Alani EE - Search Results

1

Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair.

Gorman J, Wang F, Redding S, Plys AJ, Fazio T, Wind S, Alani EE, Greene EC. Gorman J, et al. Among authors: alani ee. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):E3074-83. doi: 10.1073/pnas.1211364109. Epub 2012 Sep 24. Proc Natl Acad Sci U S A. 2012. PMID: 23012240 Free PMC article.

2

Dynamic basis for one-dimensional DNA scanning by the mismatch repair complex Msh2-Msh6.

Gorman J, Chowdhury A, Surtees JA, Shimada J, Reichman DR, Alani E, Greene EC. Gorman J, et al. Mol Cell. 2007 Nov 9;28(3):359-70. doi: 10.1016/j.molcel.2007.09.008. Mol Cell. 2007. PMID: 17996701 Free PMC article.

3

Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice.

Gorman J, Plys AJ, Visnapuu ML, Alani E, Greene EC. Gorman J, et al. Nat Struct Mol Biol. 2010 Aug;17(8):932-8. doi: 10.1038/nsmb.1858. Epub 2010 Jul 25. Nat Struct Mol Biol. 2010. PMID: 20657586 Free PMC article.

4

The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair.

Plys AJ, Rogacheva MV, Greene EC, Alani E. Plys AJ, et al. J Mol Biol. 2012 Sep 14;422(2):192-203. doi: 10.1016/j.jmb.2012.05.030. Epub 2012 May 30. J Mol Biol. 2012. PMID: 22659005 Free PMC article.

5

A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae.

Nishant KT, Plys AJ, Alani E. Nishant KT, et al. Genetics. 2008 Jun;179(2):747-55. doi: 10.1534/genetics.108.086645. Epub 2008 May 27. Genetics. 2008. PMID: 18505871 Free PMC article.

6

DNA bending and unbending by MutS govern mismatch recognition and specificity.

Wang H, Yang Y, Schofield MJ, Du C, Fridman Y, Lee SD, Larson ED, Drummond JT, Alani E, Hsieh P, Erie DA. Wang H, et al. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14822-7. doi: 10.1073/pnas.2433654100. Epub 2003 Nov 21. Proc Natl Acad Sci U S A. 2003. PMID: 14634210 Free PMC article.

7

Negative epistasis between natural variants of the Saccharomyces cerevisiae MLH1 and PMS1 genes results in a defect in mismatch repair.

Heck JA, Argueso JL, Gemici Z, Reeves RG, Bernard A, Aquadro CF, Alani E. Heck JA, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3256-61. doi: 10.1073/pnas.0510998103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492773 Free PMC article.

8

DNA replication and mismatch repair safeguard against metabolic imbalances.

Manhart CM, Alani E. Manhart CM, et al. Proc Natl Acad Sci U S A. 2017 May 30;114(22):5561-5563. doi: 10.1073/pnas.1705971114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533419 Free PMC article. No abstract available.

9

Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1.

Sugawara N, Goldfarb T, Studamire B, Alani E, Haber JE. Sugawara N, et al. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9315-20. doi: 10.1073/pnas.0305749101. Epub 2004 Jun 15. Proc Natl Acad Sci U S A. 2004. PMID: 15199178 Free PMC article.

10

Replication factors license exonuclease I in mismatch repair.

Surtees JA, Alani E. Surtees JA, et al. Mol Cell. 2004 Jul 23;15(2):164-6. doi: 10.1016/j.molcel.2004.07.004. Mol Cell. 2004. PMID: 15260965 Free article.

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