O'Brien TA - Search Results

1

GSK3 inhibition prevents lethal GVHD in mice.

Klamer G, Shen S, Song E, Rice AM, Knight R, Lindeman R, O'Brien TA, Dolnikov A. Klamer G, et al. Exp Hematol. 2013 Jan;41(1):39-55.e10. doi: 10.1016/j.exphem.2012.09.005. Epub 2012 Sep 19. Exp Hematol. 2013. PMID: 22999867

2

Glycogen synthase kinase-3beta inhibition preserves hematopoietic stem cell activity and inhibits leukemic cell growth.

Holmes T, O'Brien TA, Knight R, Lindeman R, Shen S, Song E, Symonds G, Dolnikov A. Holmes T, et al. Stem Cells. 2008 May;26(5):1288-97. doi: 10.1634/stemcells.2007-0600. Epub 2008 Mar 6. Stem Cells. 2008. PMID: 18323411

3

The role of glycogen synthase kinase-3beta in normal haematopoiesis, angiogenesis and leukaemia.

Holmes T, O'Brien TA, Knight R, Lindeman R, Symonds G, Dolnikov A. Holmes T, et al. Curr Med Chem. 2008;15(15):1493-9. doi: 10.2174/092986708784638834. Curr Med Chem. 2008. PMID: 18537625 Review.

4

siRNA targeting the IRF2 transcription factor inhibits leukaemic cell growth.

Choo A, Palladinetti P, Holmes T, Basu S, Shen S, Lock RB, O'Brien TA, Symonds G, Dolnikov A. Choo A, et al. Int J Oncol. 2008 Jul;33(1):175-83. Int J Oncol. 2008. PMID: 18575764

5

Glycogen synthase kinase--3β inhibitors suppress leukemia cell growth.

Song EY, Palladinetti P, Klamer G, Ko KH, Lindeman R, O'Brien TA, Dolnikov A. Song EY, et al. Exp Hematol. 2010 Oct;38(10):908-921.e1. doi: 10.1016/j.exphem.2010.06.001. Epub 2010 Jun 9. Exp Hematol. 2010. PMID: 20540984 Free article.

6

Using small molecule GSK3β inhibitors to treat inflammation.

Klamer G, Song E, Ko KH, O'Brien TA, Dolnikov A. Klamer G, et al. Curr Med Chem. 2010;17(26):2873-81. doi: 10.2174/092986710792065090. Curr Med Chem. 2010. PMID: 20858169 Review.

7

GSK-3β inhibition promotes engraftment of ex vivo-expanded hematopoietic stem cells and modulates gene expression.

Ko KH, Holmes T, Palladinetti P, Song E, Nordon R, O'Brien TA, Dolnikov A. Ko KH, et al. Stem Cells. 2011 Jan;29(1):108-18. doi: 10.1002/stem.551. Stem Cells. 2011. PMID: 20960517

8

Ex vivo expansion of haematopoietic stem cells to improve engraftment in stem cell transplantation.

Ko KH, Nordon R, O'Brien TA, Symonds G, Dolnikov A. Ko KH, et al. Methods Mol Biol. 2011;761:249-60. doi: 10.1007/978-1-61779-182-6_17. Methods Mol Biol. 2011. PMID: 21755454

9

Ex vivo expansion of cord blood progenitors impairs their short-term and long-term repopulating activity associated with transcriptional dysregulation of signalling networks.

Holmes T, Yan F, Ko KH, Nordon R, Song E, O'Brien TA, Dolnikov A. Holmes T, et al. Cell Prolif. 2012 Jun;45(3):266-78. doi: 10.1111/j.1365-2184.2012.00813.x. Epub 2012 Mar 20. Cell Prolif. 2012. PMID: 22429797 Free PMC article.

10

GSK-3β inhibition preserves naive T cell phenotype in bone marrow reconstituted mice.

Shen S, Klamer G, Xu N, O'Brien TA, Dolnikov A. Shen S, et al. Exp Hematol. 2013 Dec;41(12):1016-27.e1. doi: 10.1016/j.exphem.2013.08.006. Epub 2013 Sep 7. Exp Hematol. 2013. PMID: 24018603 Free article.

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