Ferone R - Search Results

1

Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.

Kelley JL, McLean EW, Cohn NK, Edelstein MP, Duch DS, Smith GK, Hanlon MH, Ferone R. Kelley JL, et al. Among authors: ferone r. J Med Chem. 1990 Feb;33(2):561-7. doi: 10.1021/jm00164a014. J Med Chem. 1990. PMID: 2299624

2

Synthesis and biological activity of open-chain analogues of 5,6,7,8-tetrahydrofolic acid--potential antitumor agents.

Bigham EC, Hodson SJ, Mallory WR, Wilson D, Duch DS, Smith GK, Ferone R. Bigham EC, et al. Among authors: ferone r. J Med Chem. 1992 Apr 17;35(8):1399-410. doi: 10.1021/jm00086a008. J Med Chem. 1992. PMID: 1573633

3

Synthesis and biological evaluation of 5-deazaisofolic acid, 5-deaza-5,6,7,8-tetrahydroisofolic acid, and their N9-substituted analogues.

Singh SK, Dev IK, Duch DS, Ferone R, Smith GK, Freisheim JH, Hynes JB. Singh SK, et al. Among authors: ferone r. J Med Chem. 1991 Feb;34(2):606-10. doi: 10.1021/jm00106a021. J Med Chem. 1991. PMID: 1995883

4

Folate analogues. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-deazahomofolic acid, and their evaluation as inhibitors of glycinamide ribonucleotide formyltransferase.

Nair MG, Murthy BR, Patil SD, Kisliuk RL, Thorndike J, Gaumont Y, Ferone R, Duch DS, Edelstein MP. Nair MG, et al. Among authors: ferone r. J Med Chem. 1989 Jun;32(6):1277-83. doi: 10.1021/jm00126a022. J Med Chem. 1989. PMID: 2498518

5

Thienyl and thiazolyl acyclic analogues of 5-deazatetrahydrofolic acid.

Hodson SJ, Bigham EC, Duch DS, Smith GK, Ferone R. Hodson SJ, et al. Among authors: ferone r. J Med Chem. 1994 Jun 24;37(13):2112-5. doi: 10.1021/jm00039a025. J Med Chem. 1994. PMID: 8027993

6

Benzo[f]quinazoline inhibitors of thymidylate synthase: methyleneamino-linked aroylglutamate derivatives.

Pendergast W, Dickerson SH, Dev IK, Ferone R, Duch DS, Smith GK. Pendergast W, et al. Among authors: ferone r. J Med Chem. 1994 Mar 18;37(6):838-44. doi: 10.1021/jm00032a019. J Med Chem. 1994. PMID: 8145235

7

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some sulfonamidobenzoylglutamate and related derivatives.

Pendergast W, Dickerson SH, Johnson JV, Dev IK, Ferone R, Duch DS, Smith GK. Pendergast W, et al. Among authors: ferone r. J Med Chem. 1993 Oct 29;36(22):3464-71. doi: 10.1021/jm00074a030. J Med Chem. 1993. PMID: 8230138

8

Benzoquinazoline inhibitors of thymidylate synthase: enzyme inhibitory activity and cytotoxicity of some 3-amino- and 3-methylbenzo[f]quinazolin-1(2H)-ones.

Pendergast W, Johnson JV, Dickerson SH, Dev IK, Duch DS, Ferone R, Hall WR, Humphreys J, Kelly JM, Wilson DC. Pendergast W, et al. Among authors: ferone r. J Med Chem. 1993 Aug 6;36(16):2279-91. doi: 10.1021/jm00068a004. J Med Chem. 1993. PMID: 8360872

9

Enhanced antitumor activity for the thymidylate synthase inhibitor 1843U89 through decreased host toxicity with oral folic acid.

Smith GK, Amyx H, Boytos CM, Duch DS, Ferone R, Wilson HR. Smith GK, et al. Among authors: ferone r. Cancer Res. 1995 Dec 15;55(24):6117-25. Cancer Res. 1995. PMID: 8521402

10

In vitro uptake, anabolism, and cellular retention of 1843U89 and other benzoquinazoline inhibitors of thymidylate synthase.

Hanlon MH, Ferone R. Hanlon MH, et al. Among authors: ferone r. Cancer Res. 1996 Jul 15;56(14):3301-6. Cancer Res. 1996. PMID: 8764125

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