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Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.
Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ, van der Hoeven B, Scholzen T, Burgdorf S, Mohrs M, Pearce EJ, Hokke CH, Haas H, Smits HH, Yazdanbakhsh M. Everts B, et al. Among authors: smits hh. J Exp Med. 2012 Sep 24;209(10):1753-67, S1. doi: 10.1084/jem.20111381. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966004 Free PMC article.
Helminth infections: protection from atopic disorders.
Smits HH, Hartgers FC, Yazdanbakhsh M. Smits HH, et al. Curr Allergy Asthma Rep. 2005 Jan;5(1):42-50. doi: 10.1007/s11882-005-0053-5. Curr Allergy Asthma Rep. 2005. PMID: 15659262 Review.
Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.
Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM, Zaat BA, Yazdanbakhsh M, Wierenga EA, van Kooyk Y, Kapsenberg ML. Smits HH, et al. J Allergy Clin Immunol. 2005 Jun;115(6):1260-7. doi: 10.1016/j.jaci.2005.03.036. J Allergy Clin Immunol. 2005. PMID: 15940144
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.
Everts B, Perona-Wright G, Smits HH, Hokke CH, van der Ham AJ, Fitzsimmons CM, Doenhoff MJ, van der Bosch J, Mohrs K, Haas H, Mohrs M, Yazdanbakhsh M, Schramm G. Everts B, et al. Among authors: smits hh. J Exp Med. 2009 Aug 3;206(8):1673-80. doi: 10.1084/jem.20082460. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635864 Free PMC article.
124 results