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Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension.
Sun B, Chamarthi B, Williams JS, Krug AW, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH. Sun B, et al. Among authors: krug aw. J Clin Endocrinol Metab. 2012 Sep;97(9):E1825-9. doi: 10.1210/jc.2012-1486. Epub 2012 Jun 20. J Clin Endocrinol Metab. 2012. PMID: 22723323 Free PMC article.
Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways.
Krug AW, Allenhöfer L, Monticone R, Spinetti G, Gekle M, Wang M, Lakatta EG. Krug AW, et al. Hypertension. 2010 Jun;55(6):1476-83. doi: 10.1161/HYPERTENSIONAHA.109.148783. Epub 2010 Apr 26. Hypertension. 2010. PMID: 20421514 Free PMC article.
42 results