Hinken A - Search Results

1

New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I.

Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. Henze M, et al. Among authors: hinken a. Biochim Biophys Acta. 2013 Apr;1833(4):823-32. doi: 10.1016/j.bbamcr.2012.08.012. Epub 2012 Aug 25. Biochim Biophys Acta. 2013. PMID: 22940544 Free PMC article.

2

Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments.

Engel PL, Hinken A, Solaro RJ. Engel PL, et al. Among authors: hinken a. J Mol Cell Cardiol. 2009 Sep;47(3):359-64. doi: 10.1016/j.yjmcc.2009.04.016. Epub 2009 May 5. J Mol Cell Cardiol. 2009. PMID: 19426736 Free PMC article.

3

Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation.

Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Scruggs SB, et al. Among authors: hinken ac. J Biol Chem. 2009 Feb 20;284(8):5097-106. doi: 10.1074/jbc.M807414200. Epub 2008 Dec 23. J Biol Chem. 2009. PMID: 19106098 Free PMC article.

4

Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments.

Lu QW, Hinken AC, Patrick SE, Solaro RJ, Kobayashi T. Lu QW, et al. J Biol Chem. 2010 Apr 16;285(16):11810-7. doi: 10.1074/jbc.M109.055657. Epub 2010 Feb 17. J Biol Chem. 2010. PMID: 20164197 Free PMC article.

5

Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A.

Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Hinken AC, et al. J Muscle Res Cell Motil. 2012 Dec;33(6):439-48. doi: 10.1007/s10974-012-9294-9. Epub 2012 Apr 22. J Muscle Res Cell Motil. 2012. PMID: 22527640 Free PMC article.

6

Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins.

Alves ML, Dias FAL, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT Rd, Sakthivel S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Alves ML, et al. Among authors: hinken ac. Circ Cardiovasc Genet. 2014 Apr;7(2):132-143. doi: 10.1161/CIRCGENETICS.113.000324. Epub 2014 Feb 28. Circ Cardiovasc Genet. 2014. PMID: 24585742 Free PMC article.

7

A dominant role of cardiac molecular motors in the intrinsic regulation of ventricular ejection and relaxation.

Hinken AC, Solaro RJ. Hinken AC, et al. Physiology (Bethesda). 2007 Apr;22:73-80. doi: 10.1152/physiol.00043.2006. Physiology (Bethesda). 2007. PMID: 17420299 Free article. Review.

8

H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling.

Avner BS, Hinken AC, Yuan C, Solaro RJ. Avner BS, et al. Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H723-30. doi: 10.1152/ajpheart.00050.2010. Epub 2010 Jun 18. Am J Physiol Heart Circ Physiol. 2010. PMID: 20562337 Free PMC article.

9

Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis.

Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Sheehan KA, et al. Among authors: hinken ac. J Mol Cell Cardiol. 2011 Mar;50(3):442-50. doi: 10.1016/j.yjmcc.2010.10.032. Epub 2010 Nov 1. J Mol Cell Cardiol. 2011. PMID: 21047515 Free PMC article.

10

Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I.

Sumandea MP, Rybin VO, Hinken AC, Wang C, Kobayashi T, Harleton E, Sievert G, Balke CW, Feinmark SJ, Solaro RJ, Steinberg SF. Sumandea MP, et al. J Biol Chem. 2008 Aug 15;283(33):22680-9. doi: 10.1074/jbc.M802396200. Epub 2008 Jun 12. J Biol Chem. 2008. PMID: 18550549 Free PMC article.

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