Lu H - Search Results

1

RECQL4 in genomic instability and aging.

Croteau DL, Singh DK, Hoh Ferrarelli L, Lu H, Bohr VA. Croteau DL, et al. Among authors: lu h. Trends Genet. 2012 Dec;28(12):624-31. doi: 10.1016/j.tig.2012.08.003. Epub 2012 Aug 30. Trends Genet. 2012. PMID: 22940096 Free PMC article. Review.

2

Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice.

Lu H, Fang EF, Sykora P, Kulikowicz T, Zhang Y, Becker KG, Croteau DL, Bohr VA. Lu H, et al. Cell Death Dis. 2014 May 15;5(5):e1226. doi: 10.1038/cddis.2014.168. Cell Death Dis. 2014. PMID: 24832598 Free PMC article.

3

RECQ helicase RECQL4 participates in non-homologous end joining and interacts with the Ku complex.

Shamanna RA, Singh DK, Lu H, Mirey G, Keijzers G, Salles B, Croteau DL, Bohr VA. Shamanna RA, et al. Among authors: lu h. Carcinogenesis. 2014 Nov;35(11):2415-24. doi: 10.1093/carcin/bgu137. Epub 2014 Jun 18. Carcinogenesis. 2014. PMID: 24942867 Free PMC article.

4

RECQL4 helicase has oncogenic potential in sporadic breast cancers.

Arora A, Agarwal D, Abdel-Fatah TM, Lu H, Croteau DL, Moseley P, Aleskandarany MA, Green AR, Ball G, Rakha EA, Chan SY, Ellis IO, Wang LL, Zhao Y, Balajee AS, Bohr VA, Madhusudan S. Arora A, et al. Among authors: lu h. J Pathol. 2016 Mar;238(4):495-501. doi: 10.1002/path.4681. Epub 2016 Feb 2. J Pathol. 2016. PMID: 26690729 Free PMC article.

5

RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.

Lu H, Shamanna RA, Keijzers G, Anand R, Rasmussen LJ, Cejka P, Croteau DL, Bohr VA. Lu H, et al. Cell Rep. 2016 Jun 28;16(1):161-173. doi: 10.1016/j.celrep.2016.05.079. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320928 Free PMC article.

6

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer.

Shamanna RA, Lu H, Croteau DL, Arora A, Agarwal D, Ball G, Aleskandarany MA, Ellis IO, Pommier Y, Madhusudan S, Bohr VA. Shamanna RA, et al. Among authors: lu h. Oncotarget. 2016 Mar 22;7(12):13269-84. doi: 10.18632/oncotarget.7906. Oncotarget. 2016. PMID: 26959889 Free PMC article.

7

WRN regulates pathway choice between classical and alternative non-homologous end joining.

Shamanna RA, Lu H, de Freitas JK, Tian J, Croteau DL, Bohr VA. Shamanna RA, et al. Among authors: lu h. Nat Commun. 2016 Dec 6;7:13785. doi: 10.1038/ncomms13785. Nat Commun. 2016. PMID: 27922005 Free PMC article.

8

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

Lu H, Shamanna RA, de Freitas JK, Okur M, Khadka P, Kulikowicz T, Holland PP, Tian J, Croteau DL, Davis AJ, Bohr VA. Lu H, et al. Nat Commun. 2017 Dec 11;8(1):2039. doi: 10.1038/s41467-017-02146-3. Nat Commun. 2017. PMID: 29229926 Free PMC article.

9

DNA-PKcs-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks.

Lu H, Guan J, Wang SY, Li GM, Bohr VA, Davis AJ. Lu H, et al. Nucleic Acids Res. 2022 Jun 10;50(10):5635-5651. doi: 10.1093/nar/gkac375. Nucleic Acids Res. 2022. PMID: 35580045 Free PMC article.

10

A research agenda for aging in China in the 21st century.

Fang EF, Scheibye-Knudsen M, Jahn HJ, Li J, Ling L, Guo H, Zhu X, Preedy V, Lu H, Bohr VA, Chan WY, Liu Y, Ng TB. Fang EF, et al. Among authors: lu h. Ageing Res Rev. 2015 Nov;24(Pt B):197-205. doi: 10.1016/j.arr.2015.08.003. Epub 2015 Aug 22. Ageing Res Rev. 2015. PMID: 26304837 Free PMC article. Review.

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