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Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, Malstrom S, Khan TM, Kung C, Skoumbourdis AP, Veith H, Southall N, Walsh MJ, Brimacombe KR, Leister W, Lunt SY, Johnson ZR, Yen KE, Kunii K, Davidson SM, Christofk HR, Austin CP, Inglese J, Harris MH, Asara JM, Stephanopoulos G, Salituro FG, Jin S, Dang L, Auld DS, Park HW, Cantley LC, Thomas CJ, Vander Heiden MG. Anastasiou D, et al. Among authors: yu y. Nat Chem Biol. 2012 Oct;8(10):839-47. doi: 10.1038/nchembio.1060. Nat Chem Biol. 2012. PMID: 22922757 Free PMC article.
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.
Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG. Israelsen WJ, et al. Among authors: yu y. Cell. 2013 Oct 10;155(2):397-409. doi: 10.1016/j.cell.2013.09.025. Cell. 2013. PMID: 24120138 Free PMC article.
Influence of acupuncture intensity on analgesic effects in AA rat models.
Wang YX, Liu YH, Zhang ZL, Qiao X, Li YC, Ren LJ, Ding GH, Yao W, Yu Y. Wang YX, et al. Among authors: yu y. Front Bioeng Biotechnol. 2024 Dec 11;12:1502535. doi: 10.3389/fbioe.2024.1502535. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 39723129 Free PMC article.
Clinical Significance of Serum Bile Acid Profiles in Fatty Liver.
Sun HY, Wu LC, Xu MJ, Zheng ED, Yu YC, Ye Y. Sun HY, et al. Among authors: yu yc. Diabetes Metab Syndr Obes. 2024 Dec 20;17:4843-4856. doi: 10.2147/DMSO.S494810. eCollection 2024. Diabetes Metab Syndr Obes. 2024. PMID: 39722833 Free PMC article.
Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1(2H)-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma.
Li QQ, Quan X, Wang ZX, Qiao N, Ni XF, Jing XL, Zhou SS, Tian XL, Zheng GC, Zhan KN, Xu YJ, Yang J, Zhou Y, Liang XT, Zhao ZH, Wei TH, Liu Q, Bai MY, Sun SL, Yu YC, Cao P, Li NG, Zhang XM, Liu J, Shi ZH. Li QQ, et al. Among authors: yu yc. J Med Chem. 2024 Dec 25. doi: 10.1021/acs.jmedchem.4c01548. Online ahead of print. J Med Chem. 2024. PMID: 39722476
According to the manufactuDHAV-1 3C protein promotes virus proliferation by antagonizing type I interferon by upregulating the ANXA2 protein.
Zhang R, Wang M, Cheng A, Yang Q, Ou X, Sun D, Tian B, He Y, Wu Z, Huang J, Wu Y, Zhang S, Zhao X, Yu Y, Zhang L, Zhu D, Jia R, Chen S, Liu M. Zhang R, et al. Among authors: yu y. Int J Biol Macromol. 2024 Dec 23:139040. doi: 10.1016/j.ijbiomac.2024.139040. Online ahead of print. Int J Biol Macromol. 2024. PMID: 39722380
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