Asara JM - Search Results

1

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, Malstrom S, Khan TM, Kung C, Skoumbourdis AP, Veith H, Southall N, Walsh MJ, Brimacombe KR, Leister W, Lunt SY, Johnson ZR, Yen KE, Kunii K, Davidson SM, Christofk HR, Austin CP, Inglese J, Harris MH, Asara JM, Stephanopoulos G, Salituro FG, Jin S, Dang L, Auld DS, Park HW, Cantley LC, Thomas CJ, Vander Heiden MG. Anastasiou D, et al. Among authors: asara jm. Nat Chem Biol. 2012 Oct;8(10):839-47. doi: 10.1038/nchembio.1060. Nat Chem Biol. 2012. PMID: 22922757 Free PMC article.

2

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO.

Abbott DW, Wilkins A, Asara JM, Cantley LC. Abbott DW, et al. Among authors: asara jm. Curr Biol. 2004 Dec 29;14(24):2217-27. doi: 10.1016/j.cub.2004.12.032. Curr Biol. 2004. PMID: 15620648 Free article.

3

In-Gel Stable-Isotope Labeling (ISIL): a strategy for mass spectrometry-based relative quantification.

Asara JM, Zhang X, Zheng B, Christofk HH, Wu N, Cantley LC. Asara JM, et al. J Proteome Res. 2006 Jan;5(1):155-63. doi: 10.1021/pr050334t. J Proteome Res. 2006. PMID: 16396506

4

In-gel stable isotope labeling for relative quantification using mass spectrometry.

Asara JM, Zhang X, Zheng B, Maroney LA, Christofk HR, Wu N, Cantley LC. Asara JM, et al. Nat Protoc. 2006;1(1):46-51. doi: 10.1038/nprot.2006.7. Nat Protoc. 2006. PMID: 17406210

5

Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry.

Asara JM, Schweitzer MH, Freimark LM, Phillips M, Cantley LC. Asara JM, et al. Science. 2007 Apr 13;316(5822):280-5. doi: 10.1126/science.1137614. Science. 2007. PMID: 17431180

6

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway.

Hutti JE, Turk BE, Asara JM, Ma A, Cantley LC, Abbott DW. Hutti JE, et al. Among authors: asara jm. Mol Cell Biol. 2007 Nov;27(21):7451-61. doi: 10.1128/MCB.01101-07. Epub 2007 Aug 20. Mol Cell Biol. 2007. PMID: 17709380 Free PMC article.

7

A label-free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen.

Asara JM, Christofk HR, Freimark LM, Cantley LC. Asara JM, et al. Proteomics. 2008 Mar;8(5):994-9. doi: 10.1002/pmic.200700426. Proteomics. 2008. PMID: 18324724

8

Pyruvate kinase M2 is a phosphotyrosine-binding protein.

Christofk HR, Vander Heiden MG, Wu N, Asara JM, Cantley LC. Christofk HR, et al. Among authors: asara jm. Nature. 2008 Mar 13;452(7184):181-6. doi: 10.1038/nature06667. Nature. 2008. PMID: 18337815

9

Molecular phylogenetics of mastodon and Tyrannosaurus rex.

Organ CL, Schweitzer MH, Zheng W, Freimark LM, Cantley LC, Asara JM. Organ CL, et al. Among authors: asara jm. Science. 2008 Apr 25;320(5875):499. doi: 10.1126/science.1154284. Science. 2008. PMID: 18436782

10

Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation.

Zheng B, Jeong JH, Asara JM, Yuan YY, Granter SR, Chin L, Cantley LC. Zheng B, et al. Among authors: asara jm. Mol Cell. 2009 Jan 30;33(2):237-47. doi: 10.1016/j.molcel.2008.12.026. Mol Cell. 2009. PMID: 19187764 Free PMC article.

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