Smits WK - Search Results

1

TcdC does not significantly repress toxin expression in Clostridium difficile 630ΔErm.

Bakker D, Smits WK, Kuijper EJ, Corver J. Bakker D, et al. Among authors: smits wk. PLoS One. 2012;7(8):e43247. doi: 10.1371/journal.pone.0043247. Epub 2012 Aug 17. PLoS One. 2012. PMID: 22912837 Free PMC article.

2

C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA.

Rosenbusch KE, Bakker D, Kuijper EJ, Smits WK. Rosenbusch KE, et al. Among authors: smits wk. PLoS One. 2012;7(10):e48608. doi: 10.1371/journal.pone.0048608. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23119071 Free PMC article.

3

Hype or hypervirulence: a reflection on problematic C. difficile strains.

Smits WK. Smits WK. Virulence. 2013 Oct 1;4(7):592-6. doi: 10.4161/viru.26297. Epub 2013 Sep 10. Virulence. 2013. PMID: 24060961 Free PMC article. Review.

4

The HtrA-like protease CD3284 modulates virulence of Clostridium difficile.

Bakker D, Buckley AM, de Jong A, van Winden VJ, Verhoeks JP, Kuipers OP, Douce GR, Kuijper EJ, Smits WK, Corver J. Bakker D, et al. Among authors: smits wk. Infect Immun. 2014 Oct;82(10):4222-32. doi: 10.1128/IAI.02336-14. Epub 2014 Jul 21. Infect Immun. 2014. PMID: 25047848 Free PMC article.

5

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5.

van Eijk E, Anvar SY, Browne HP, Leung WY, Frank J, Schmitz AM, Roberts AP, Smits WK. van Eijk E, et al. Among authors: smits wk. BMC Genomics. 2015 Jan 31;16(1):31. doi: 10.1186/s12864-015-1252-7. BMC Genomics. 2015. PMID: 25636331 Free PMC article.

6

Clostridium difficile infection.

Smits WK, Lyras D, Lacy DB, Wilcox MH, Kuijper EJ. Smits WK, et al. Nat Rev Dis Primers. 2016 Apr 7;2:16020. doi: 10.1038/nrdp.2016.20. Nat Rev Dis Primers. 2016. PMID: 27158839 Free PMC article. Review.

7

SNP-ing out the differences: Investigating differences between Clostridium difficile lab strains.

Smits WK. Smits WK. Virulence. 2017 Aug 18;8(6):613-617. doi: 10.1080/21505594.2016.1250998. Epub 2016 Oct 28. Virulence. 2017. PMID: 27791481 Free PMC article. No abstract available.

8

DNA replication proteins as potential targets for antimicrobials in drug-resistant bacterial pathogens.

van Eijk E, Wittekoek B, Kuijper EJ, Smits WK. van Eijk E, et al. Among authors: smits wk. J Antimicrob Chemother. 2017 May 1;72(5):1275-1284. doi: 10.1093/jac/dkw548. J Antimicrob Chemother. 2017. PMID: 28073967 Free PMC article. Review.

9

A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile.

Smits WK, Weese JS, Roberts AP, Harmanus C, Hornung B. Smits WK, et al. Anaerobe. 2018 Feb;49:78-84. doi: 10.1016/j.anaerobe.2017.12.005. Epub 2017 Dec 12. Anaerobe. 2018. PMID: 29246842 Free article.

10

The evolving epidemic of Clostridium difficile 630.

Roberts AP, Smits WK. Roberts AP, et al. Among authors: smits wk. Anaerobe. 2018 Oct;53:2-4. doi: 10.1016/j.anaerobe.2018.04.015. Epub 2018 Apr 27. Anaerobe. 2018. PMID: 29730161

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