Vernachio JH - Search Results

1

A recombinant clumping factor A-containing vaccine induces functional antibodies to Staphylococcus aureus that are not observed after natural exposure.

Hawkins J, Kodali S, Matsuka YV, McNeil LK, Mininni T, Scully IL, Vernachio JH, Severina E, Girgenti D, Jansen KU, Anderson AS, Donald RG. Hawkins J, et al. Among authors: vernachio jh. Clin Vaccine Immunol. 2012 Oct;19(10):1641-50. doi: 10.1128/CVI.00354-12. Epub 2012 Aug 15. Clin Vaccine Immunol. 2012. PMID: 22896688 Free PMC article.

2

Characterization of a protective monoclonal antibody recognizing Staphylococcus aureus MSCRAMM protein clumping factor A.

Hall AE, Domanski PJ, Patel PR, Vernachio JH, Syribeys PJ, Gorovits EL, Johnson MA, Ross JM, Hutchins JT, Patti JM. Hall AE, et al. Among authors: vernachio jh. Infect Immun. 2003 Dec;71(12):6864-70. doi: 10.1128/IAI.71.12.6864-6870.2003. Infect Immun. 2003. PMID: 14638774 Free PMC article.

3

Characterization of a humanized monoclonal antibody recognizing clumping factor A expressed by Staphylococcus aureus.

Domanski PJ, Patel PR, Bayer AS, Zhang L, Hall AE, Syribeys PJ, Gorovits EL, Bryant D, Vernachio JH, Hutchins JT, Patti JM. Domanski PJ, et al. Among authors: vernachio jh. Infect Immun. 2005 Aug;73(8):5229-32. doi: 10.1128/IAI.73.8.5229-5232.2005. Infect Immun. 2005. PMID: 16041045 Free PMC article.

4

A panel of monoclonal antibodies recognizing the Staphylococcus epidermidis fibrinogen-binding MSCRAMM SdrG.

Hall AE, Patel PR, Domanski PJ, Prater BD, Gorovits EL, Syribeys PJ, Vernachio JH, Patti JM, Hutchins JT. Hall AE, et al. Among authors: vernachio jh. Hybridoma (Larchmt). 2007 Feb;26(1):28-34. doi: 10.1089/hyb.2006.039. Hybridoma (Larchmt). 2007. PMID: 17316083

5

Anti-clumping factor A immunoglobulin reduces the duration of methicillin-resistant Staphylococcus aureus bacteremia in an experimental model of infective endocarditis.

Vernachio J, Bayer AS, Le T, Chai YL, Prater B, Schneider A, Ames B, Syribeys P, Robbins J, Patti JM. Vernachio J, et al. Antimicrob Agents Chemother. 2003 Nov;47(11):3400-6. doi: 10.1128/AAC.47.11.3400-3406.2003. Antimicrob Agents Chemother. 2003. PMID: 14576094 Free PMC article.

6

Human immunoglobulin G recognizing fibrinogen-binding surface proteins is protective against both Staphylococcus aureus and Staphylococcus epidermidis infections in vivo.

Vernachio JH, Bayer AS, Ames B, Bryant D, Prater BD, Syribeys PJ, Gorovits EL, Patti JM. Vernachio JH, et al. Antimicrob Agents Chemother. 2006 Feb;50(2):511-8. doi: 10.1128/AAC.50.2.511-518.2006. Antimicrob Agents Chemother. 2006. PMID: 16436704 Free PMC article.

7

Inhibition of complement activation by a secreted Staphylococcus aureus protein.

Lee LY, Höök M, Haviland D, Wetsel RA, Yonter EO, Syribeys P, Vernachio J, Brown EL. Lee LY, et al. J Infect Dis. 2004 Aug 1;190(3):571-9. doi: 10.1086/422259. Epub 2004 Jul 6. J Infect Dis. 2004. PMID: 15243934

8

SdrX, a serine-aspartate repeat protein expressed by Staphylococcus capitis with collagen VI binding activity.

Liu Y, Ames B, Gorovits E, Prater BD, Syribeys P, Vernachio JH, Patti JM. Liu Y, et al. Among authors: vernachio jh. Infect Immun. 2004 Nov;72(11):6237-44. doi: 10.1128/IAI.72.11.6237-6244.2004. Infect Immun. 2004. PMID: 15501749 Free PMC article.

9

Monoclonal antibodies recognizing the Enterococcus faecalis collagen-binding MSCRAMM Ace: conditional expression and binding analysis.

Hall AE, Gorovits EL, Syribeys PJ, Domanski PJ, Ames BR, Chang CY, Vernachio JH, Patti JM, Hutchins JT. Hall AE, et al. Among authors: vernachio jh. Microb Pathog. 2007 Aug-Sep;43(2-3):55-66. doi: 10.1016/j.micpath.2007.03.003. Epub 2007 Apr 19. Microb Pathog. 2007. PMID: 17521860

10

INX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.

Vernachio JH, Bleiman B, Bryant KD, Chamberlain S, Hunley D, Hutchins J, Ames B, Gorovits E, Ganguly B, Hall A, Kolykhalov A, Liu Y, Muhammad J, Raja N, Walters CR, Wang J, Williams K, Patti JM, Henson G, Madela K, Aljarah M, Gilles A, McGuigan C. Vernachio JH, et al. Antimicrob Agents Chemother. 2011 May;55(5):1843-51. doi: 10.1128/AAC.01335-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357300 Free PMC article.

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