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Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.
Slominski AT, Janjetovic Z, Fuller BE, Zmijewski MA, Tuckey RC, Nguyen MN, Sweatman T, Li W, Zjawiony J, Miller D, Chen TC, Lozanski G, Holick MF. Slominski AT, et al. Among authors: sweatman t. PLoS One. 2010 Mar 26;5(3):e9907. doi: 10.1371/journal.pone.0009907. PLoS One. 2010. PMID: 20360850 Free PMC article.
Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc.
Tuckey RC, Li W, Zjawiony JK, Zmijewski MA, Nguyen MN, Sweatman T, Miller D, Slominski A. Tuckey RC, et al. Among authors: sweatman t. FEBS J. 2008 May;275(10):2585-96. doi: 10.1111/j.1742-4658.2008.06406.x. Epub 2008 Apr 10. FEBS J. 2008. PMID: 18410379 Free PMC article.
80 results