Chen J - Search Results

1

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes.

Slominski AT, Kim TK, Chen J, Nguyen MN, Li W, Yates CR, Sweatman T, Janjetovic Z, Tuckey RC. Slominski AT, et al. Among authors: chen j. Int J Biochem Cell Biol. 2012 Nov;44(11):2003-18. doi: 10.1016/j.biocel.2012.07.027. Epub 2012 Aug 2. Int J Biochem Cell Biol. 2012. PMID: 22877869 Free PMC article.

2

Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma.

Chen J, Wang Z, Lu Y, Dalton JT, Miller DD, Li W. Chen J, et al. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3183-7. doi: 10.1016/j.bmcl.2008.04.073. Epub 2008 May 1. Bioorg Med Chem Lett. 2008. PMID: 18477505 Free PMC article.

3

Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells.

Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Zmijewski MA, et al. Among authors: chen j. Steroids. 2009 Feb;74(2):218-28. doi: 10.1016/j.steroids.2008.10.017. Epub 2008 Nov 6. Steroids. 2009. PMID: 19028513 Free PMC article.

4

Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives.

Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Zmijewski MA, et al. Among authors: chen j. Photochem Photobiol Sci. 2008 Dec;7(12):1570-6. doi: 10.1039/b809005j. Epub 2008 Sep 4. Photochem Photobiol Sci. 2008. PMID: 19037511 Free PMC article.

5

Discovery of 4-substituted methoxybenzoyl-aryl-thiazole as novel anticancer agents: synthesis, biological evaluation, and structure-activity relationships.

Lu Y, Li CM, Wang Z, Ross CR 2nd, Chen J, Dalton JT, Li W, Miller DD. Lu Y, et al. Among authors: chen j. J Med Chem. 2009 Mar 26;52(6):1701-11. doi: 10.1021/jm801449a. J Med Chem. 2009. PMID: 19243174 Free PMC article.

6

Structure elucidation of major metabolites from medroxyprogesterone acetate by P450.

Chen J, Zhang JW, Yang L, Li W. Chen J, et al. Chem Pharm Bull (Tokyo). 2009 Aug;57(8):835-9. doi: 10.1248/cpb.57.835. Chem Pharm Bull (Tokyo). 2009. PMID: 19652409 Free article.

7

A new steroidal 5,7-diene derivative, 3beta-hydroxyandrosta-5,7-diene-17beta-carboxylic acid, shows potent anti-proliferative activity.

Kim TK, Chen J, Li W, Zjawiony J, Miller D, Janjetovic Z, Tuckey RC, Slominski A. Kim TK, et al. Among authors: chen j. Steroids. 2010 Mar;75(3):230-9. doi: 10.1016/j.steroids.2009.12.004. Epub 2009 Dec 16. Steroids. 2010. PMID: 20025893 Free PMC article.

8

Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents.

Lu Y, Wang Z, Li CM, Chen J, Dalton JT, Li W, Miller DD. Lu Y, et al. Among authors: chen j. Bioorg Med Chem. 2010 Jan 15;18(2):477-95. doi: 10.1016/j.bmc.2009.12.020. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20056548 Free PMC article.

9

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity.

Li W, Chen J, Janjetovic Z, Kim TK, Sweatman T, Lu Y, Zjawiony J, Tuckey RC, Miller D, Slominski A. Li W, et al. Among authors: chen j. Steroids. 2010 Dec;75(12):926-35. doi: 10.1016/j.steroids.2010.05.021. Epub 2010 Jun 11. Steroids. 2010. PMID: 20542050 Free PMC article.

10

Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents.

Chen J, Wang Z, Li CM, Lu Y, Vaddady PK, Meibohm B, Dalton JT, Miller DD, Li W. Chen J, et al. J Med Chem. 2010 Oct 28;53(20):7414-27. doi: 10.1021/jm100884b. J Med Chem. 2010. PMID: 20919720 Free PMC article.

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