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Page 1
Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.
Bussenius J, Blazey CM, Aay N, Anand NK, Arcalas A, Baik T, Bowles OJ, Buhr CA, Costanzo S, Curtis JK, DeFina SC, Dubenko L, Heuer TS, Huang P, Jaeger C, Joshi A, Kennedy AR, Kim AI, Lara K, Lee J, Li J, Lougheed JC, Ma S, Malek S, Manalo JC, Martini JF, McGrath G, Nicoll M, Nuss JM, Pack M, Peto CJ, Tsang TH, Wang L, Womble SW, Yakes M, Zhang W, Rice KD. Bussenius J, et al. Among authors: lara k. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5396-404. doi: 10.1016/j.bmcl.2012.07.052. Epub 2012 Jul 21. Bioorg Med Chem Lett. 2012. PMID: 22877636
Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).
Takeuchi CS, Kim BG, Blazey CM, Ma S, Johnson HW, Anand NK, Arcalas A, Baik TG, Buhr CA, Cannoy J, Epshteyn S, Joshi A, Lara K, Lee MS, Wang L, Leahy JW, Nuss JM, Aay N, Aoyama R, Foster P, Lee J, Lehoux I, Munagala N, Plonowski A, Rajan S, Woolfrey J, Yamaguchi K, Lamb P, Miller N. Takeuchi CS, et al. Among authors: lara k. J Med Chem. 2013 Mar 28;56(6):2218-34. doi: 10.1021/jm3007933. Epub 2013 Mar 7. J Med Chem. 2013. PMID: 23394126
Thiourea-Based Receptors for Anion Recognition and Signaling.
Gomez-Vega J, Vasquez-Cornejo A, Juárez-Sánchez O, Corona-Martínez DO, Ochoa-Terán A, López-Gastelum KA, Sotelo-Mundo RR, Santacruz-Ortega H, Gálvez-Ruiz JC, Pérez-González R, Lara KO. Gomez-Vega J, et al. Among authors: lara ko. ACS Omega. 2024 Jan 17;9(4):4412-4422. doi: 10.1021/acsomega.3c06861. eCollection 2024 Jan 30. ACS Omega. 2024. PMID: 38313514 Free PMC article.
Integrable Systems and Spacetime Dynamics.
Cárdenas M, Correa F, Lara K, Pino M. Cárdenas M, et al. Among authors: lara k. Phys Rev Lett. 2021 Oct 15;127(16):161601. doi: 10.1103/PhysRevLett.127.161601. Phys Rev Lett. 2021. PMID: 34723615
35 results