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Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide.
Murineddu G, Lazzari P, Ruiu S, Sanna A, Loriga G, Manca I, Falzoi M, Dessì C, Curzu MM, Chelucci G, Pani L, Pinna GA. Murineddu G, et al. Among authors: falzoi m. J Med Chem. 2006 Dec 14;49(25):7502-12. doi: 10.1021/jm060920d. J Med Chem. 2006. PMID: 17149879
Novel diazabicycloalkane delta opioid agonists.
Loriga G, Lazzari P, Manca I, Ruiu S, Falzoi M, Murineddu G, Bottazzi ME, Pinna G, Pinna GA. Loriga G, et al. Among authors: falzoi m. Bioorg Med Chem. 2015 Sep 1;23(17):5527-38. doi: 10.1016/j.bmc.2015.07.036. Epub 2015 Jul 27. Bioorg Med Chem. 2015. PMID: 26252963
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.
Lazzari P, Distinto R, Manca I, Baillie G, Murineddu G, Pira M, Falzoi M, Sani M, Morales P, Ross R, Zanda M, Jagerovic N, Pinna GA. Lazzari P, et al. Among authors: falzoi m. Eur J Med Chem. 2016 Oct 4;121:194-208. doi: 10.1016/j.ejmech.2016.05.011. Epub 2016 May 6. Eur J Med Chem. 2016. PMID: 27240274
38 results