Parnell SC - Search Results

1

Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity.

Hao N, Yildirim N, Nagiec MJ, Parnell SC, Errede B, Dohlman HG, Elston TC. Hao N, et al. Among authors: parnell sc. Mol Biol Cell. 2012 Oct;23(19):3899-910. doi: 10.1091/mbc.E12-04-0333. Epub 2012 Aug 8. Mol Biol Cell. 2012. PMID: 22875986 Free PMC article.

2

Phosphorylation of the RGS protein Sst2 by the MAP kinase Fus3 and use of Sst2 as a model to analyze determinants of substrate sequence specificity.

Parnell SC, Marotti LA Jr, Kiang L, Torres MP, Borchers CH, Dohlman HG. Parnell SC, et al. Biochemistry. 2005 Jun 7;44(22):8159-66. doi: 10.1021/bi0503091. Biochemistry. 2005. PMID: 15924435

3

Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae.

Chasse SA, Flanary P, Parnell SC, Hao N, Cha JY, Siderovski DP, Dohlman HG. Chasse SA, et al. Among authors: parnell sc. Eukaryot Cell. 2006 Feb;5(2):330-46. doi: 10.1128/EC.5.2.330-346.2006. Eukaryot Cell. 2006. PMID: 16467474 Free PMC article.

4

A systems-biology analysis of feedback inhibition in the Sho1 osmotic-stress-response pathway.

Hao N, Behar M, Parnell SC, Torres MP, Borchers CH, Elston TC, Dohlman HG. Hao N, et al. Among authors: parnell sc. Curr Biol. 2007 Apr 17;17(8):659-67. doi: 10.1016/j.cub.2007.02.044. Epub 2007 Mar 15. Curr Biol. 2007. PMID: 17363249 Free article.

5

The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast.

Zeller CE, Parnell SC, Dohlman HG. Zeller CE, et al. Among authors: parnell sc. J Biol Chem. 2007 Aug 24;282(34):25168-76. doi: 10.1074/jbc.M702569200. Epub 2007 Jun 25. J Biol Chem. 2007. PMID: 17591772 Free article.

6

Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.

Parnell SC, Magenheimer BS, Maser RL, Zien CA, Frischauf AM, Calvet JP. Parnell SC, et al. J Biol Chem. 2002 May 31;277(22):19566-72. doi: 10.1074/jbc.M201875200. Epub 2002 Mar 23. J Biol Chem. 2002. PMID: 11912216 Free article.

7

Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain.

Parnell SC, Magenheimer BS, Maser RL, Calvet JP. Parnell SC, et al. Biochem Biophys Res Commun. 1999 Jun 16;259(3):539-43. doi: 10.1006/bbrc.1999.0810. Biochem Biophys Res Commun. 1999. PMID: 10364454

8

Protein phosphatase-1α interacts with and dephosphorylates polycystin-1.

Parnell SC, Puri S, Wallace DP, Calvet JP. Parnell SC, et al. PLoS One. 2012;7(6):e36798. doi: 10.1371/journal.pone.0036798. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675472 Free PMC article.

9

A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.

Parnell SC, Magenheimer BS, Maser RL, Pavlov TS, Havens MA, Hastings ML, Jackson SF, Ward CJ, Peterson KR, Staruschenko A, Calvet JP. Parnell SC, et al. Hum Mol Genet. 2018 Oct 1;27(19):3313-3324. doi: 10.1093/hmg/ddy223. Hum Mol Genet. 2018. PMID: 29931260 Free PMC article.

10

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro.

Parnell SC, Magenheimer BS, Maser RL, Rankin CA, Smine A, Okamoto T, Calvet JP. Parnell SC, et al. Biochem Biophys Res Commun. 1998 Oct 20;251(2):625-31. doi: 10.1006/bbrc.1998.9514. Biochem Biophys Res Commun. 1998. PMID: 9792824

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