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Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity.
Saenger S, Holtmann B, Nilges MR, Schroeder S, Hoeflich A, Kletzl H, Spooren W, Ostrowitzki S, Hanania T, Sendtner M, Metzger F. Saenger S, et al. Among authors: spooren w. Amyotroph Lateral Scler. 2012 Sep;13(5):418-29. doi: 10.3109/17482968.2012.679944. Epub 2012 Aug 7. Amyotroph Lateral Scler. 2012. PMID: 22871074
Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder.
Brunner D, Kabitzke P, He D, Cox K, Thiede L, Hanania T, Sabath E, Alexandrov V, Saxe M, Peles E, Mills A, Spooren W, Ghosh A, Feliciano P, Benedetti M, Luo Clayton A, Biemans B. Brunner D, et al. Among authors: spooren w. PLoS One. 2015 Aug 14;10(8):e0134572. doi: 10.1371/journal.pone.0134572. eCollection 2015. PLoS One. 2015. PMID: 26273832 Free PMC article.
Comprehensive analysis of two Shank3 and the Cacna1c mouse models of autism spectrum disorder.
Kabitzke PA, Brunner D, He D, Fazio PA, Cox K, Sutphen J, Thiede L, Sabath E, Hanania T, Alexandrov V, Rasmusson R, Spooren W, Ghosh A, Feliciano P, Biemans B, Benedetti M, Clayton AL. Kabitzke PA, et al. Among authors: spooren w. Genes Brain Behav. 2018 Jan;17(1):4-22. doi: 10.1111/gbb.12405. Epub 2017 Sep 5. Genes Brain Behav. 2018. PMID: 28753255 Free article.
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Michalon A, Sidorov M, Ballard TM, Ozmen L, Spooren W, Wettstein JG, Jaeschke G, Bear MF, Lindemann L. Michalon A, et al. Among authors: spooren w. Neuron. 2012 Apr 12;74(1):49-56. doi: 10.1016/j.neuron.2012.03.009. Neuron. 2012. PMID: 22500629 Free PMC article.
Mouse models of alpha-synucleinopathy and Lewy pathology.
Sommer B, Barbieri S, Hofele K, Wiederhold K, Probst A, Mistl C, Danner S, Kauffmann S, Spooren W, Tolnay M, Bilbe G, van der Putten H, Kafmann S, Caromi P, Ruegg MA. Sommer B, et al. Among authors: spooren w. Exp Gerontol. 2000 Dec;35(9-10):1389-403. doi: 10.1016/s0531-5565(00)00181-9. Exp Gerontol. 2000. PMID: 11113617
Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).
Schuler V, Lüscher C, Blanchet C, Klix N, Sansig G, Klebs K, Schmutz M, Heid J, Gentry C, Urban L, Fox A, Spooren W, Jaton AL, Vigouret J, Pozza M, Kelly PH, Mosbacher J, Froestl W, Käslin E, Korn R, Bischoff S, Kaupmann K, van der Putten H, Bettler B. Schuler V, et al. Among authors: spooren w. Neuron. 2001 Jul 19;31(1):47-58. doi: 10.1016/s0896-6273(01)00345-2. Neuron. 2001. PMID: 11498050 Free article.
115 results