Bakkenist CJ - Search Results

1

Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.

Yamamoto K, Wang Y, Jiang W, Liu X, Dubois RL, Lin CS, Ludwig T, Bakkenist CJ, Zha S. Yamamoto K, et al. Among authors: bakkenist cj. J Cell Biol. 2012 Aug 6;198(3):305-13. doi: 10.1083/jcb.201204098. J Cell Biol. 2012. PMID: 22869596 Free PMC article.

2

The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy.

Vendetti FP, Pandya P, Clump DA, Schamus-Haynes S, Tavakoli M, diMayorca M, Islam NM, Chang J, Delgoffe GM, Beumer JH, Bakkenist CJ. Vendetti FP, et al. Among authors: bakkenist cj. JCI Insight. 2023 Feb 22;8(4):e165615. doi: 10.1172/jci.insight.165615. JCI Insight. 2023. PMID: 36810257 Free PMC article.

3

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.

Karlseder J, Hoke K, Mirzoeva OK, Bakkenist C, Kastan MB, Petrini JH, de Lange T. Karlseder J, et al. PLoS Biol. 2004 Aug;2(8):E240. doi: 10.1371/journal.pbio.0020240. Epub 2004 Aug 17. PLoS Biol. 2004. PMID: 15314656 Free PMC article.

4

ATM activation in normal human tissues and testicular cancer.

Bartkova J, Bakkenist CJ, Rajpert-De Meyts E, Skakkebaek NE, Sehested M, Lukas J, Kastan MB, Bartek J. Bartkova J, et al. Among authors: bakkenist cj. Cell Cycle. 2005 Jun;4(6):838-45. doi: 10.4161/cc.4.6.1742. Epub 2005 Jun 13. Cell Cycle. 2005. PMID: 15846060

5

Irreversible chromosome damage accumulates rapidly in the absence of ATM kinase activity.

White JS, Choi S, Bakkenist CJ. White JS, et al. Among authors: bakkenist cj. Cell Cycle. 2008 May 1;7(9):1277-84. doi: 10.4161/cc.7.9.5961. Epub 2008 Mar 18. Cell Cycle. 2008. PMID: 18418045

6

Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange.

White JS, Choi S, Bakkenist CJ. White JS, et al. Among authors: bakkenist cj. Sci Signal. 2010 Jun 1;3(124):ra44. doi: 10.1126/scisignal.2000758. Sci Signal. 2010. PMID: 20516478 Free PMC article.

7

Inhibition of ATM kinase activity does not phenocopy ATM protein disruption: implications for the clinical utility of ATM kinase inhibitors.

Choi S, Gamper AM, White JS, Bakkenist CJ. Choi S, et al. Among authors: bakkenist cj. Cell Cycle. 2010 Oct 15;9(20):4052-7. doi: 10.4161/cc.9.20.13471. Epub 2010 Oct 27. Cell Cycle. 2010. PMID: 20953138 Free PMC article.

8

The ATM kinase signaling induced by the low-energy β-particles emitted by (33)P is essential for the suppression of chromosome aberrations and is greater than that induced by the energetic β-particles emitted by (32)P.

White JS, Yue N, Hu J, Bakkenist CJ. White JS, et al. Among authors: bakkenist cj. Mutat Res. 2011 Mar 15;708(1-2):28-36. doi: 10.1016/j.mrfmmm.2011.01.005. Epub 2011 Feb 16. Mutat Res. 2011. PMID: 21315088 Free PMC article.

9

Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.

Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S. Menolfi D, et al. Among authors: bakkenist cj. Nat Commun. 2018 Dec 17;9(1):5351. doi: 10.1038/s41467-018-07798-3. Nat Commun. 2018. PMID: 30559436 Free PMC article.

10

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.

Horejsí Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J. Horejsí Z, et al. Among authors: bakkenist cj. Oncogene. 2004 Apr 15;23(17):3122-7. doi: 10.1038/sj.onc.1207447. Oncogene. 2004. PMID: 15048089

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