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Page 1
Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities.
Hara-Yokoyama M, Kukimoto-Niino M, Terasawa K, Harumiya S, Podyma-Inoue KA, Hino N, Sakamoto K, Itoh S, Hashii N, Hiruta Y, Kawasaki N, Mishima-Tsumagari C, Kaitsu Y, Matsumoto T, Wakiyama M, Shirouzu M, Kasama T, Takayanagi H, Utsunomiya-Tate N, Takatsu K, Katada T, Hirabayashi Y, Yokoyama S, Yanagishita M. Hara-Yokoyama M, et al. Structure. 2012 Sep 5;20(9):1585-95. doi: 10.1016/j.str.2012.06.017. Epub 2012 Aug 2. Structure. 2012. PMID: 22863568 Free article.
Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.
Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, Chow CR, Shirouzu M, Terada T, Patel M, Yokoyama S, Kozasa T. Hajicek N, et al. J Biol Chem. 2011 Jun 10;286(23):20625-36. doi: 10.1074/jbc.M110.201392. Epub 2011 Apr 20. J Biol Chem. 2011. PMID: 21507947 Free PMC article.
Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Hanawa-Suetsugu K, Kukimoto-Niino M, Mishima-Tsumagari C, Akasaka R, Ohsawa N, Sekine S, Ito T, Tochio N, Koshiba S, Kigawa T, Terada T, Shirouzu M, Nishikimi A, Uruno T, Katakai T, Kinashi T, Kohda D, Fukui Y, Yokoyama S. Hanawa-Suetsugu K, et al. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3305-10. doi: 10.1073/pnas.1113512109. Epub 2012 Feb 13. Proc Natl Acad Sci U S A. 2012. PMID: 22331897 Free PMC article.
Reduced efficacy of a Src kinase inhibitor in crowded protein solution.
Kasahara K, Re S, Nawrocki G, Oshima H, Mishima-Tsumagari C, Miyata-Yabuki Y, Kukimoto-Niino M, Yu I, Shirouzu M, Feig M, Sugita Y. Kasahara K, et al. Among authors: mishima tsumagari c. Nat Commun. 2021 Jul 2;12(1):4099. doi: 10.1038/s41467-021-24349-5. Nat Commun. 2021. PMID: 34215742 Free PMC article.
Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Tam C, Kukimoto-Niino M, Miyata-Yabuki Y, Tsuda K, Mishima-Tsumagari C, Ihara K, Inoue M, Yonemochi M, Hanada K, Matsumoto T, Shirouzu M, Zhang KYJ. Tam C, et al. Among authors: mishima tsumagari c. Commun Biol. 2023 Mar 17;6(1):284. doi: 10.1038/s42003-023-04657-w. Commun Biol. 2023. PMID: 36932164 Free PMC article.
RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
Kukimoto-Niino M, Katsura K, Ishizuka-Katsura Y, Mishima-Tsumagari C, Yonemochi M, Inoue M, Nakagawa R, Kaushik R, Zhang KYJ, Shirouzu M. Kukimoto-Niino M, et al. Among authors: mishima tsumagari c. J Biol Chem. 2024 Jul;300(7):107459. doi: 10.1016/j.jbc.2024.107459. Epub 2024 Jun 8. J Biol Chem. 2024. PMID: 38857861 Free PMC article.
19 results