Daly RJ - Search Results

1

Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors.

Wöhrle FU, Halbach S, Aumann K, Schwemmers S, Braun S, Auberger P, Schramek D, Penninger JM, Laßmann S, Werner M, Waller CF, Pahl HL, Zeiser R, Daly RJ, Brummer T. Wöhrle FU, et al. Among authors: daly rj. Leukemia. 2013 Jan;27(1):118-29. doi: 10.1038/leu.2012.222. Epub 2012 Aug 3. Leukemia. 2013. PMID: 22858987

2

How to Grb2 a Gab.

Wöhrle FU, Daly RJ, Brummer T. Wöhrle FU, et al. Among authors: daly rj. Structure. 2009 Jun 10;17(6):779-81. doi: 10.1016/j.str.2009.05.003. Structure. 2009. PMID: 19523893 Free article.

3

Function, regulation and pathological roles of the Gab/DOS docking proteins.

Wöhrle FU, Daly RJ, Brummer T. Wöhrle FU, et al. Among authors: daly rj. Cell Commun Signal. 2009 Sep 8;7:22. doi: 10.1186/1478-811X-7-22. Cell Commun Signal. 2009. PMID: 19737390 Free PMC article.

4

Docking proteins.

Brummer T, Schmitz-Peiffer C, Daly RJ. Brummer T, et al. Among authors: daly rj. FEBS J. 2010 Nov;277(21):4356-69. doi: 10.1111/j.1742-4658.2010.07865.x. Epub 2010 Sep 30. FEBS J. 2010. PMID: 20883498 Free article. Review.

5

Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein.

Brummer T, Schramek D, Hayes VM, Bennett HL, Caldon CE, Musgrove EA, Daly RJ. Brummer T, et al. Among authors: daly rj. J Biol Chem. 2006 Jan 6;281(1):626-37. doi: 10.1074/jbc.M509567200. Epub 2005 Oct 27. J Biol Chem. 2006. PMID: 16253990 Free article.

6

Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis.

Bennett HL, Brummer T, Jeanes A, Yap AS, Daly RJ. Bennett HL, et al. Among authors: daly rj. Oncogene. 2008 Apr 24;27(19):2693-704. doi: 10.1038/sj.onc.1210928. Epub 2007 Nov 12. Oncogene. 2008. PMID: 17998934

7

Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development.

Fleuren ED, O'Toole S, Millar EK, McNeil C, Lopez-Knowles E, Boulghourjian A, Croucher DR, Schramek D, Brummer T, Penninger JM, Sutherland RL, Daly RJ. Fleuren ED, et al. Among authors: daly rj. Int J Cancer. 2010 Sep 1;127(6):1486-92. doi: 10.1002/ijc.25172. Int J Cancer. 2010. PMID: 20087860

8

Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Brummer T, Larance M, Herrera Abreu MT, Lyons RJ, Timpson P, Emmerich CH, Fleuren ED, Lehrbach GM, Schramek D, Guilhaus M, James DE, Daly RJ. Brummer T, et al. Among authors: daly rj. EMBO J. 2008 Sep 3;27(17):2305-16. doi: 10.1038/emboj.2008.159. EMBO J. 2008. PMID: 19172738 Free PMC article.

9

Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation.

Herrera Abreu MT, Hughes WE, Mele K, Lyons RJ, Rickwood D, Browne BC, Bennett HL, Vallotton P, Brummer T, Daly RJ. Herrera Abreu MT, et al. Among authors: daly rj. Mol Biol Cell. 2011 Jan 1;22(1):105-16. doi: 10.1091/mbc.E10-03-0185. Epub 2010 Nov 30. Mol Biol Cell. 2011. PMID: 21118992 Free PMC article.

10

DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs.

Patterson KI, Brummer T, Daly RJ, O'Brien PM. Patterson KI, et al. Among authors: daly rj. Biochim Biophys Acta. 2010 Sep;1803(9):1003-12. doi: 10.1016/j.bbamcr.2010.03.014. Epub 2010 Mar 27. Biochim Biophys Acta. 2010. PMID: 20347885 Free article.

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