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Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
van Erp NP, Eechoute K, van der Veldt AA, Haanen JB, Reyners AK, Mathijssen RH, Boven E, van der Straaten T, Baak-Pablo RF, Wessels JA, Guchelaar HJ, Gelderblom H. van Erp NP, et al. Among authors: reyners ak. J Clin Oncol. 2009 Sep 10;27(26):4406-12. doi: 10.1200/JCO.2008.21.7679. Epub 2009 Aug 10. J Clin Oncol. 2009. PMID: 19667267
Myelosuppression by sunitinib is flt-3 genotype dependent.
van Erp NP, Mathijssen RH, van der Veldt AA, Haanen JB, Reyners AK, Eechoute K, Boven E, Wessels JA, Guchelaar HJ, Gelderblom H. van Erp NP, et al. Among authors: reyners ak. Br J Cancer. 2010 Aug 24;103(5):757-8. doi: 10.1038/sj.bjc.6605813. Epub 2010 Aug 3. Br J Cancer. 2010. PMID: 20683446 Free PMC article. No abstract available.
Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension.
Eechoute K, van der Veldt AA, Oosting S, Kappers MH, Wessels JA, Gelderblom H, Guchelaar HJ, Reyners AK, van Herpen CM, Haanen JB, Mathijssen RH, Boven E. Eechoute K, et al. Among authors: reyners ak. Clin Pharmacol Ther. 2012 Oct;92(4):503-10. doi: 10.1038/clpt.2012.136. Epub 2012 Sep 5. Clin Pharmacol Ther. 2012. PMID: 22948895
A phase IIb multicentre study comparing the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma: the TRUSTS trial.
Bui-Nguyen B, Butrynski JE, Penel N, Blay JY, Isambert N, Milhem M, Kerst JM, Reyners AK, Litière S, Marréaud S, Collin F, van der Graaf WT; European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group (EORTC/STBSG) and the Sarcoma Alliance for Research through Collaboration (SARC). Bui-Nguyen B, et al. Among authors: reyners ak. Eur J Cancer. 2015 Jul;51(10):1312-20. doi: 10.1016/j.ejca.2015.03.023. Epub 2015 Apr 23. Eur J Cancer. 2015. PMID: 25912752 Clinical Trial.
173 results