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Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, Macconaill L, Hanna M, Hahn WC, Lue NF, Reddel RR, Jiao Y, Kinzler K, Vogelstein B, Papadopoulos N, Meeker AK; ALT Starr Cancer Consortium. Lovejoy CA, et al. Among authors: papadopoulos n. PLoS Genet. 2012;8(7):e1002772. doi: 10.1371/journal.pgen.1002772. Epub 2012 Jul 19. PLoS Genet. 2012. PMID: 22829774 Free PMC article.
Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.
Lagerstedt Robinson K, Liu T, Vandrovcova J, Halvarsson B, Clendenning M, Frebourg T, Papadopoulos N, Kinzler KW, Vogelstein B, Peltomäki P, Kolodner RD, Nilbert M, Lindblom A. Lagerstedt Robinson K, et al. Among authors: papadopoulos n. J Natl Cancer Inst. 2007 Feb 21;99(4):291-9. doi: 10.1093/jnci/djk051. J Natl Cancer Inst. 2007. PMID: 17312306
A multidimensional analysis of genes mutated in breast and colorectal cancers.
Lin J, Gan CM, Zhang X, Jones S, Sjöblom T, Wood LD, Parsons DW, Papadopoulos N, Kinzler KW, Vogelstein B, Parmigiani G, Velculescu VE. Lin J, et al. Among authors: papadopoulos n. Genome Res. 2007 Sep;17(9):1304-18. doi: 10.1101/gr.6431107. Epub 2007 Aug 10. Genome Res. 2007. PMID: 17693572 Free PMC article.
The antisense transcriptomes of human cells.
He Y, Vogelstein B, Velculescu VE, Papadopoulos N, Kinzler KW. He Y, et al. Among authors: papadopoulos n. Science. 2008 Dec 19;322(5909):1855-7. doi: 10.1126/science.1163853. Epub 2008 Dec 4. Science. 2008. PMID: 19056939 Free PMC article.
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, Rajagopalan H, Schmidt K, Willson JK, Markowitz S, Zhou S, Diaz LA Jr, Velculescu VE, Lengauer C, Kinzler KW, Vogelstein B, Papadopoulos N. Yun J, et al. Among authors: papadopoulos n. Science. 2009 Sep 18;325(5947):1555-9. doi: 10.1126/science.1174229. Epub 2009 Aug 6. Science. 2009. PMID: 19661383 Free PMC article.
Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation.
Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Ericson K, et al. Among authors: papadopoulos n. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2598-603. doi: 10.1073/pnas.0914018107. Epub 2010 Jan 20. Proc Natl Acad Sci U S A. 2010. PMID: 20133737 Free PMC article.
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells.
He Y, Wu J, Dressman DC, Iacobuzio-Donahue C, Markowitz SD, Velculescu VE, Diaz LA Jr, Kinzler KW, Vogelstein B, Papadopoulos N. He Y, et al. Among authors: papadopoulos n. Nature. 2010 Mar 25;464(7288):610-4. doi: 10.1038/nature08802. Epub 2010 Mar 3. Nature. 2010. PMID: 20200521 Free PMC article.
1,647 results