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Influenza A viruses target type II pneumocytes in the human lung.
Weinheimer VK, Becher A, Tönnies M, Holland G, Knepper J, Bauer TT, Schneider P, Neudecker J, Rückert JC, Szymanski K, Temmesfeld-Wollbrueck B, Gruber AD, Bannert N, Suttorp N, Hippenstiel S, Wolff T, Hocke AC. Weinheimer VK, et al. Among authors: ruckert jc. J Infect Dis. 2012 Dec 1;206(11):1685-94. doi: 10.1093/infdis/jis455. Epub 2012 Jul 24. J Infect Dis. 2012. PMID: 22829640 Free PMC article.
Reply to Fujino et al.
Hocke AC, Berg J, Becher A, Knepper J, Klauschen F, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Gruber AD, Suttorp N, Hippenstiel S, Wolff T. Hocke AC, et al. Among authors: ruckert jc. J Infect Dis. 2013 Feb 15;207(4):693-5. doi: 10.1093/infdis/jis740. Epub 2012 Nov 29. J Infect Dis. 2013. PMID: 23204172 No abstract available.
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs.
Hocke AC, Becher A, Knepper J, Peter A, Holland G, Tönnies M, Bauer TT, Schneider P, Neudecker J, Muth D, Wendtner CM, Rückert JC, Drosten C, Gruber AD, Laue M, Suttorp N, Hippenstiel S, Wolff T. Hocke AC, et al. Among authors: ruckert jc. Am J Respir Crit Care Med. 2013 Oct 1;188(7):882-6. doi: 10.1164/rccm.201305-0954LE. Am J Respir Crit Care Med. 2013. PMID: 24083868 No abstract available.
Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia.
Müller-Redetzky HC, Wienhold SM, Berg J, Hocke AC, Hippenstiel S, Hellwig K, Gutbier B, Opitz B, Neudecker J, Rückert J, Gruber AD, Kershaw O, Mayer K, Suttorp N, Witzenrath M. Müller-Redetzky HC, et al. J Antimicrob Chemother. 2015 Mar;70(3):830-40. doi: 10.1093/jac/dku446. Epub 2014 Nov 17. J Antimicrob Chemother. 2015. PMID: 25406299
Tyk2 as a target for immune regulation in human viral/bacterial pneumonia.
Berg J, Zscheppang K, Fatykhova D, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Eggeling S, Schimek M, Gruber AD, Suttorp N, Hippenstiel S, Hocke AC. Berg J, et al. Among authors: ruckert jc. Eur Respir J. 2017 Jul 13;50(1):1601953. doi: 10.1183/13993003.01953-2016. Print 2017 Jul. Eur Respir J. 2017. PMID: 28705941 Free article.
Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.
Nerlich A, Mieth M, Letsiou E, Fatykhova D, Zscheppang K, Imai-Matsushima A, Meyer TF, Paasch L, Mitchell TJ, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Eggeling S, Schimek M, Witzenrath M, Suttorp N, Hippenstiel S, Hocke AC. Nerlich A, et al. Among authors: ruckert jc. Sci Rep. 2018 Jan 9;8(1):182. doi: 10.1038/s41598-017-18468-7. Sci Rep. 2018. PMID: 29317705 Free PMC article.
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke K, Obermayer B, Mache C, Fatykhova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Graff P, Schulze J, Mieth M, Hellwig K, Demir Z, Biere B, Brunotte L, Mecate-Zambrano A, Bushe J, Dohmen M, Hinze C, Elezkurtaj S, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Schmidt-Ott KM, Busch J, Klauschen F, Horst D, Radbruch H, Radke J, Heppner F, Corman VM, Niemeyer D, Müller MA, Goffinet C, Mothes R, Pascual-Reguant A, Hauser AE, Beule D, Landthaler M, Ludwig S, Suttorp N, Witzenrath M, Gruber AD, Drosten C, Sander LE, Wolff T, Hippenstiel S, Hocke AC. Hönzke K, et al. Among authors: ruckert jc. Eur Respir J. 2022 Dec 1;60(6):2102725. doi: 10.1183/13993003.02725-2021. Print 2022 Dec. Eur Respir J. 2022. PMID: 35728978 Free PMC article.
Human alveolar progenitors generate dual lineage bronchioalveolar organoids.
Hoffmann K, Obermayer B, Hönzke K, Fatykhova D, Demir Z, Löwa A, Alves LGT, Wyler E, Lopez-Rodriguez E, Mieth M, Baumgardt M, Hoppe J, Firsching TC, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Gruber AD, Ochs M, Landthaler M, Beule D, Suttorp N, Hippenstiel S, Hocke AC, Kessler M. Hoffmann K, et al. Among authors: ruckert jc. Commun Biol. 2022 Aug 25;5(1):875. doi: 10.1038/s42003-022-03828-5. Commun Biol. 2022. PMID: 36008580 Free PMC article.
88 results